• Type: Stimulant, Respiratory Stimulant, Nonselective Phosphodiesterase Enzyme Inhibitor
  • Dosage Forms: tablets, capsules, lozenges, oral solution, injectable solution
  • Dosage Strengths: tablets: 200 mg; capsules: 200 mg; lozenges: 75 mg; oral solution: 20 mg/mL; injectable solution: 20 mg/mL
  • Routes of Administration: PO, IV, IM
  • Common Trade Names: NoDoz, Recharge, Vivarin, Diurex, Cafcit

Common Dosages by Type

Type Amount Caffeine^
Coffee, brewed 1 cup 100mg
Coffee, instant 1 cup 75mg
Tea 1 cup 50mg
Red Bull 1 can 80mg
Rockstar 1 can 160mg
Excedrin Migraine 2 tabs 130mg

^Average caffeine content can vary[1][2]

Adult Dosing

Pediatric Dosing

Special Populations

  • Pregnancy Rating:
  • Lactation:
  • Renal Dosing
    • Adult
    • Pediatric
  • Hepatic Dosing
    • Adult
    • Pediatric


  • Allergy to class/drug

Adverse Reactions


  • Half-life: 5 hours
  • Metabolism: Liver CYP450
  • Excretion: Urine
  • Mechanism of Action: Adenosine receptor antagonist

Mechanism of Action

  • Methylxanthine structure that antagonizes adenosine receptors

See Also


  1. Food Standards Agency (2001) Statement on the Reproductive Effects of Caffeine. London: Food Standards Agency.
  2. Juliano LM and Griffiths RR. Caffeine. In Lowinson, J.H., Ruiz, P., Millman, R.B., Langrod, J.G. (Eds.). Substance Abuse: A Comprehensive Textbook, Fourth Edition. 2005. PP. 403-421. Baltimore: Lippincott, Williams, & Wilkins.