Thyroid disease (main): Difference between revisions

Latest revision as of 22:34, 17 December 2019

Background

Spectrum of Thyroid Disease

Thyroid physiology: Hypothalamus (top) releases TRH; causing pituitary gland (second from top) to release TSH; causing thyroid gland (third from top) to make T3 and T4; inhibition loops also shown.

Myxedema coma << hypothyroidism < euthyroid > hyperthyroidism >> thyroid storm

Clinical Features

Differential Diagnosis

Evaluation

Management

Disposition

References

Sharma AN, Levy DL; Thyroid and Adrenal Disorders; in Marx JA, Hockberger RS, Walls RM, et al (eds): Rosen’s Emergency Medicine: Concepts and Clinical Practice, ed 8. St. Louis, Mosby, Inc., 2014, (Ch) 128: p 1676-1693.
Agus, MSD: Chapter 86 – Endocrine Emergencies, in Fleisher & Ludwig’s Textbook of Pediatric EM, 6th Ed., Lippincott Williams & Williams, 2010, p. 779-780

Authors:

@@ Line 1: / Line 1: @@
 ==Background==
+{{Thyroid gen background}}
+==Clinical Features==
-Spectrum of Disease
+==Differential Diagnosis==
-Hypo <--> Hyper
+==Evaluation==
+[[File:thyroid studies.JPG|px200]]
-myxedema coma << hypothyroid < euthyroid < hyperthyroid << thyroid storm
+==Management==
+==Disposition==
-Other
-- cretinism- no congenital t3/t4
-- parafollicular C cells make calcitonin to keep the bone in
-- endemic goiter- if pt from area c low iodine I intake
-- free t3 & t4 determines thyroid state- not total plasma conc
-- t4-> t3 active & rt3 inactive
-- trh -> tsh -> t4 ->t3. t3 I's pittry
-hthal pitutry gland
-- thyroid state changes dtr relax and contract speed and bmr O2 use.
 ==See Also==
+*[[Thyroid Storm]]
+*[[Hyperthyroidism]]
+*[[Myxedema Coma]]
+*[[Hypothyroidism]]
+==References==
+*Sharma AN, Levy DL; Thyroid and Adrenal Disorders; in Marx JA, Hockberger RS, Walls RM, et al (eds): Rosen’s Emergency Medicine: Concepts and Clinical Practice, ed 8. St. Louis, Mosby, Inc., 2014, (Ch) 128: p 1676-1693.
+*Agus, MSD: Chapter 86 – Endocrine Emergencies, in Fleisher & Ludwig’s Textbook of Pediatric EM, 6th Ed., Lippincott Williams & Williams, 2010, p. 779-780
-Endo: Thyroid Storm
+[[Category:Endocrinology]]
-Endo: Hyperthyroidism
-Endo: Myxedema Coma
-Endo: Hypothyroidism
-[[Category:Endo]]