Cyclopentolate: Difference between revisions
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Latest revision as of 21:56, 20 March 2026
Administration
- Type: Cycloplegic, topical anticholinergics
- Dosage Forms:
- Routes of Administration: Ophthalmic
- Common Trade Names: Cyclogyl, Cylate, Pentolair
Adult Dosing
- 1-2 drops of 0.5%-2% solution, may repeat in 5-10min if needed
Pediatric Dosing
- Small infants: 1 drop of 0.5%-2% solution
- Children: 1-2 drops of 0.5%-2% solution, may repeat with 0.5%-1% solution in 5-10min if needed
Special Populations
- Pregnancy Rating: C
- Lactation risk: infant risk cannot be ruled out
- Renal dosing
- Hepatic dosing
Contraindications
- Allergy to class/drug
- Narrow-angle glaucoma or anatomically narrow angles
Adverse Reactions
Serious
- Tachyarrythmia, vasodilation
- Seizure
- Ataxia, confusion, psychosis
- Conjunctivitis
- Raised intraocular pressure
Common
- Blurred vision
- Burning sensation in eye
- Photophobia
Pharmacology
- Half-life:
- Metabolism:
- Excretion:
Mechanism of Action
- Anticholinergic, blocks the responses of the sphincter muscle of the iris and stimulation of ciliary body muscle, leading to cycloplegia and mydriasis.
Comments
Indications by Condition
The following table is automatically generated from disease/condition pages across WikEM.
| Indication | Dose | Context | Route | Population |
|---|---|---|---|---|
| Corneal abrasion | 1 drop 1% q6-8hr | Cycloplegic for large abrasions (>2mm) and/or severe pain | Topical ophthalmic | Adult |