Metoprolol: Difference between revisions
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Latest revision as of 21:55, 20 March 2026
General
- Type: Beta blockers
- Dosage Forms: Tablet: 25 mg, 37.5 mg, 50 mg, 75mg, 100 mg. IV: variable
- Common Trade Names: Lopressor
Adult Dosing
Hypertension
- 50-200 mg PO bid
CHF
- 12.5-100 mg PO bid
Migraine prophylaxis
- 25-100 mg PO bid
Pediatric Dosing
Special Populations
- Pregnancy Rating: C
- Lactation:
- Renal Dosing
- Adult: No adjustment necessary
- Pediatric: No adjustment necessary
- Hepatic Dosing
- Adult: Not defined however consider reduced dose due to hepatic metabolism
- Pediatric: Not defined however consider reduced dose due to hepatic metabolism
Contraindications
- Allergy to class/drug
- Sinus bradycardia
- AV blocks
- decompensated acute CHF
- cardiogenic shock
- hypotension
Adverse Reactions
Serious
- CHF
- bradycardia
- AV block
- bronchospasm
Common
- fatigue
- dizziness
- depression
- dyspnea
Pharmacology
- Half-life: 3-7 hours
- Metabolism: Liver
- Excretion: Renal
- Mechanism of Action: Selective Beta-1 adrenergic receptor antagonist
Indications by Condition
The following table is automatically generated from disease/condition pages across WikEM.
| Indication | Dose | Context | Route | Population |
|---|---|---|---|---|
| Atrial fibrillation (main) | 5 mg IV q5min x3 | Rate control (1st line beta-blocker) | IV | Adult |
| Atrial fibrillation with RVR | 5mg IV q5min x3 | Rate control (beta-blocker) | IV | Adult |
| Paroxysmal supraventricular tachycardia | 5 mg IV q5min x3; then 50 mg PO if effective | Beta-blocker | IV/PO | Adult |
See Also
References
Metoprolol: Drug information. UpToDate. www.uptodate.com. Accessed April 2, 2019.