Traditional chinese medicine toxicology: Difference between revisions

 
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==Major Groups==
==Background==
* Aconitine Group
*Traditional Chinese medicine has become increasingly popular in the US and other Western countries, and has remained extremely popular in China and Hong Kong.<ref name="Kam">Kam PC1, Liew S. Traditional Chinese herbal medicine and anaesthesia. Anaesthesia. 2002 Nov;57(11):1083-9.</ref>
**Cardiotoxicity (ventricular arrhythmia + hypotension)
*Although generally marketed as "natural" and "herbal" in nature, many contain contaminants in the form of heavy metals or conventional western medications.<ref name="Kam" />
*Podophyllin Group
**Studies have found, among others, cadmium, cobalt, copper, iron, manganese, nickel, lead, zinc, and mercury in traditional Chinese medicines<ref name="Kam" /><ref name="Chan">Chan K. Some aspects of toxic contaminants in herbal medicines. Chemosphere. 2003 Sep;52(9):1361-71.</ref>
**Neurotoxicity (convulsion + coma)
 
*Anticholinergic group
==Common Toxic Herbs==
**Tachy arrythmia + altered mental status
===Aconitine Group===
*Digoxin-like agents
''These are the most common group of herbals<ref name="Kam" />
*Other
*Activates sodium channels → cardiac and neurotoxicity
*[[Paresthesia]]s, [[nausea/vomiting]], [[arrhythmias]], [[hypotension]]
===Podophyllin Group===
*Neurotoxicity ([[seizure]] + [[coma]])
===Anticholinergic group===
*[[Tachyarrhythmias]] + [[altered mental status]]
===[[Digoxin]]-like agents===
*[[Tachyarrhythmias]]
*[[Heart block]]


==See Also==
==See Also==
*[[Toxicology (Main)]]
*[[Toxicology (Main)]]


==Source==
==References==
EPI
<references/>


[[Category:Drugs]]
[[Category:Pharmacology]]
[[Category:Tox]]
[[Category:Toxicology]]

Latest revision as of 23:06, 23 September 2019

Background

  • Traditional Chinese medicine has become increasingly popular in the US and other Western countries, and has remained extremely popular in China and Hong Kong.[1]
  • Although generally marketed as "natural" and "herbal" in nature, many contain contaminants in the form of heavy metals or conventional western medications.[1]
    • Studies have found, among others, cadmium, cobalt, copper, iron, manganese, nickel, lead, zinc, and mercury in traditional Chinese medicines[1][2]

Common Toxic Herbs

Aconitine Group

These are the most common group of herbals[1]

Podophyllin Group

Anticholinergic group

Digoxin-like agents

See Also

References

  1. 1.0 1.1 1.2 1.3 Kam PC1, Liew S. Traditional Chinese herbal medicine and anaesthesia. Anaesthesia. 2002 Nov;57(11):1083-9.
  2. Chan K. Some aspects of toxic contaminants in herbal medicines. Chemosphere. 2003 Sep;52(9):1361-71.