Topical steroids: Difference between revisions

(Created page with "==Background== *The USA system utilizes 7 classes, which are classified by their ability to constrict capillaries *Class I is the strongest and Class VII is the weakest<ref>Ha...")
 
 
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*Class I is the strongest and Class VII is the weakest<ref>Habif, Thomas P. (1990). Clinical dermatology: a color guide to diagnosis and therapy (2nd ed.). St. Louis: Mosby. p. Inside front cover. ISBN 0-8016-2465-7.</ref>
*Class I is the strongest and Class VII is the weakest<ref>Habif, Thomas P. (1990). Clinical dermatology: a color guide to diagnosis and therapy (2nd ed.). St. Louis: Mosby. p. Inside front cover. ISBN 0-8016-2465-7.</ref>


== Classification==
==Classification==
===Group I===
===Group I===
Very potent: up to 600 times stronger than [[hydrocortisone]]
Very potent: up to 600 times stronger than [[hydrocortisone]]
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===Group VII===
===Group VII===
The weakest class of topical steroids. Has poor lipid permeability, and can not penetrate mucous membranes well.
The weakest class of topical steroids. Has poor lipid permeability, and can not penetrate mucous membranes well.
*Hydrocortisone 2.5% (Hytone cream, lotion, ointment)
*[[Hydrocortisone]] 2.5% (Hytone cream, lotion, ointment)
*Hydrocortisone 1% (Many over-the-counter brands)
*[[Hydrocortisone]] 1% (Many over-the-counter brands)
 
==Topical Steroid Potency Ranking<ref>Fang J. Dermatology. In: The Harriet Lane Handbook. 20th ed. Philadelphia, PA: Elsevier; 2015</ref>==
{| {{table}}
| align="center" style="background:#f0f0f0;"|'''Brand name'''
| align="center" style="background:#f0f0f0;"|'''Generic name'''
|-
| '''CLASS 1—Superpotent'''||
|-
| Clobex Lotion/Spray/Shampoo, 0.05%||Clobetasol propionate
|-
| Cordran Tape, 0.05%||Flurandrenolide
|-
| Cormax Cream/Solution, 0.05%||Clobetasol propionate
|-
| Diprolene Ointment, 0.05%||Betamethasone dipropionate
|-
| Olux E Foam, 0.05%||Clobetasol propionate
|-
| Olux Foam, 0.05%||Clobetasol propionate
|-
| Psorcon Ointment, 0.05%||Diflorasone diacetate
|-
| Psorcon E Ointment, 0.05%||Diflorasone diacetate
|-
| Temovate Cream/Ointment/Solution, 0.05%||Clobetasol propionate
|-
| Topicort Topical Spray, 0.25%||Desoximetasone
|-
| Ultravate Cream/Ointment, 0.05%||Halobetasol propionate
|-
| Ultravate Lotion, 0.05%||Halobetasol propionate
|-
| Vanos Cream, 0.1%||Fluocinonide
|-
| '''CLASS 2—Potent'''||
|-
| Diprolene Cream AF, 0.05%||Betamethasone dipropionate
|-
| Elocon Ointment, 0.1%||Mometasone furoate
|-
| Florone Ointment, 0.05%||Diflorasone diacetate
|-
| Halog Ointment/Cream, 0.1%||Halcinonide
|-
| Lidex Cream/Gel/Ointment, 0.05%||Fluocinonide
|-
| Psorcon Cream, 0.05%||Diflorasone diacetate
|-
| Topicort Cream/Ointment, 0.25%||Desoximetasone
|-
| Topicort Gel, 0.05%||Desoximetasone
|-
| '''CLASS 3—Upper Mid-Strength'''||
|-
| Cutivate Ointment, 0.005%||Fluticasone propionate
|-
| Lidex-E Cream, 0.05%||Fluocinonide
|-
| Luxiq Foam, 0.12%||Betamethasone valerate
|-
| '''CLASS 4—Mid-Strength'''||
|-
| Cordran Ointment, 0.05%||Flurandrenolide
|-
| Elocon Cream, 0.1%||Mometasone furoate
|-
| Kenalog Cream/Spray, 0.1%||Triamcinolone acetonide
|-
| Synalar Ointment, 0.03%||Fluocinolone acetonide
|-
| Topicort LP Cream, 0.05%||Desoximetasone
|-
| Topicort LP Ointment, 0.05%||Desoximetasone
|-
| Westcort Ointment, 0.2%||Hydrocortisone valerate
|-
| '''CLASS 5—Lower Mid-Strength'''||
|-
| Capex Shampoo, 0.01%||Fluocinolone acetonide
|-
| Cordran Cream/Lotion/Tape, 0.05%||Flurandrenolide
|-
| Cutivate Cream/Lotion, 0.05%||Fluticasone propionate
|-
| DermAtop Cream, 0.1%||Prednicarbate
|-
| DesOwen Lotion, 0.05%||Desonide
|-
| Locoid Cream/Lotion/Ointment/Solution, 0.1%||Hydrocortisone
|-
| Pandel Cream, 0.1%||Hydrocortisone
|-
| Synalar Cream, 0.03%/0.01%||Fluocinolone acetonide
|-
| Westcort Cream, 0.2%||Hydrocortisone valerate
|-
| '''CLASS 6—Mild'''||
|-
| Aclovate Cream/Ointment, 0.05%||Alclometasone dipropionate
|-
| Derma-Smoothe/FS Oil, 0.01%||Fluocinolone acetonide
|-
| Desonate Gel, 0.05%||Desonide
|-
| Synalar Cream/Solution, 0.01%||Fluocinolone acetonide
|-
| Verdeso Foam, 0.05%||Desonide
|-
| '''CLASS 7—Least Potent'''||
|-
| Cetacort Lotion, 0.5%/1%||Hydrocortisone
|-
| Cortaid Cream/Spray/Ointment||Hydrocortisone
|-
| Hytone Cream/Lotion, 1%/2.5%||Hydrocortisone
|-
| Micort-HC Cream, 2%/2.5%||Hydrocortisone
|-
| Nutracort Lotion, 1%/2.5%||Hydrocortisone
|-
| Synacort Cream, 1%/2.5%||Hydrocortisone
|}


==See Also==
==See Also==
*[[Corticosteroids]]
*[[Corticosteroids]]
==References==
<references/>
[[Category:Pharmacology]]
[[Category:Dermatology]]

Latest revision as of 00:53, 5 June 2017

Background

  • The USA system utilizes 7 classes, which are classified by their ability to constrict capillaries
  • Class I is the strongest and Class VII is the weakest[1]

Classification

Group I

Very potent: up to 600 times stronger than hydrocortisone

Group II

Group III

Group IV

Group V

Group VI

Group VII

The weakest class of topical steroids. Has poor lipid permeability, and can not penetrate mucous membranes well.

Topical Steroid Potency Ranking[2]

Brand name Generic name
CLASS 1—Superpotent
Clobex Lotion/Spray/Shampoo, 0.05% Clobetasol propionate
Cordran Tape, 0.05% Flurandrenolide
Cormax Cream/Solution, 0.05% Clobetasol propionate
Diprolene Ointment, 0.05% Betamethasone dipropionate
Olux E Foam, 0.05% Clobetasol propionate
Olux Foam, 0.05% Clobetasol propionate
Psorcon Ointment, 0.05% Diflorasone diacetate
Psorcon E Ointment, 0.05% Diflorasone diacetate
Temovate Cream/Ointment/Solution, 0.05% Clobetasol propionate
Topicort Topical Spray, 0.25% Desoximetasone
Ultravate Cream/Ointment, 0.05% Halobetasol propionate
Ultravate Lotion, 0.05% Halobetasol propionate
Vanos Cream, 0.1% Fluocinonide
CLASS 2—Potent
Diprolene Cream AF, 0.05% Betamethasone dipropionate
Elocon Ointment, 0.1% Mometasone furoate
Florone Ointment, 0.05% Diflorasone diacetate
Halog Ointment/Cream, 0.1% Halcinonide
Lidex Cream/Gel/Ointment, 0.05% Fluocinonide
Psorcon Cream, 0.05% Diflorasone diacetate
Topicort Cream/Ointment, 0.25% Desoximetasone
Topicort Gel, 0.05% Desoximetasone
CLASS 3—Upper Mid-Strength
Cutivate Ointment, 0.005% Fluticasone propionate
Lidex-E Cream, 0.05% Fluocinonide
Luxiq Foam, 0.12% Betamethasone valerate
CLASS 4—Mid-Strength
Cordran Ointment, 0.05% Flurandrenolide
Elocon Cream, 0.1% Mometasone furoate
Kenalog Cream/Spray, 0.1% Triamcinolone acetonide
Synalar Ointment, 0.03% Fluocinolone acetonide
Topicort LP Cream, 0.05% Desoximetasone
Topicort LP Ointment, 0.05% Desoximetasone
Westcort Ointment, 0.2% Hydrocortisone valerate
CLASS 5—Lower Mid-Strength
Capex Shampoo, 0.01% Fluocinolone acetonide
Cordran Cream/Lotion/Tape, 0.05% Flurandrenolide
Cutivate Cream/Lotion, 0.05% Fluticasone propionate
DermAtop Cream, 0.1% Prednicarbate
DesOwen Lotion, 0.05% Desonide
Locoid Cream/Lotion/Ointment/Solution, 0.1% Hydrocortisone
Pandel Cream, 0.1% Hydrocortisone
Synalar Cream, 0.03%/0.01% Fluocinolone acetonide
Westcort Cream, 0.2% Hydrocortisone valerate
CLASS 6—Mild
Aclovate Cream/Ointment, 0.05% Alclometasone dipropionate
Derma-Smoothe/FS Oil, 0.01% Fluocinolone acetonide
Desonate Gel, 0.05% Desonide
Synalar Cream/Solution, 0.01% Fluocinolone acetonide
Verdeso Foam, 0.05% Desonide
CLASS 7—Least Potent
Cetacort Lotion, 0.5%/1% Hydrocortisone
Cortaid Cream/Spray/Ointment Hydrocortisone
Hytone Cream/Lotion, 1%/2.5% Hydrocortisone
Micort-HC Cream, 2%/2.5% Hydrocortisone
Nutracort Lotion, 1%/2.5% Hydrocortisone
Synacort Cream, 1%/2.5% Hydrocortisone

See Also

References

  1. ↑ Habif, Thomas P. (1990). Clinical dermatology: a color guide to diagnosis and therapy (2nd ed.). St. Louis: Mosby. p. Inside front cover. ISBN 0-8016-2465-7.
  2. ↑ Fang J. Dermatology. In: The Harriet Lane Handbook. 20th ed. Philadelphia, PA: Elsevier; 2015
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