Parvovirus B19: Difference between revisions
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==Clinical Features== | ==Clinical Features== | ||
*[[Erythema infectiosum (fifth disease)]] | *[[Erythema infectiosum (fifth disease)]] | ||
*Most contagious during the phase of active viral replication and viral shedding, which occurs approximately 5 to 10 days after exposure and usually lasts approximately 5 days | |||
*Complications | *Complications | ||
**Arthropathy | **Arthropathy | ||
**[[Aplastic | **[[Aplastic anemia]] | ||
==Differential Diagnosis== | ==Differential Diagnosis== | ||
*[[Roseola]] | |||
*[[Measles]] | |||
*[[Rubella]] | |||
*Enteroviral infections | |||
*Group A Streptococcal infections | |||
== | ==Evaluation== | ||
*Diagnosis is clinical usually through clinical presentation | |||
*IgM testing is recommended for immunocompromised patients. | |||
==Management== | ==Management== | ||
Latest revision as of 10:59, 24 July 2016
Background
- In children: causes Erythema infectiosum (Fifth disease)
- In transplant patients on immunosuppressive drugs: causes RBC aplasia.
- Short-lived, may not be discovered
- Parvovirus only replicated in erythroid progenitor cells
Clinical Features
- Erythema infectiosum (fifth disease)
- Most contagious during the phase of active viral replication and viral shedding, which occurs approximately 5 to 10 days after exposure and usually lasts approximately 5 days
- Complications
- Arthropathy
- Aplastic anemia
Differential Diagnosis
Evaluation
- Diagnosis is clinical usually through clinical presentation
- IgM testing is recommended for immunocompromised patients.
Management
- Parvovirus is usually self-limiting and requires no further treatment.
- Management should be targeted at reducing symptoms, such as using anti-inflammatory medications for arthropathy or performing transfusions for aplastic anemia.
Disposition
See Also
External Links
References
- Fish RM, Massad MG. The Transplant Patient. In: Tintinalli JE, Stapczynski J, Ma O, Cline DM, Cydulka RK, Meckler GD, T. eds. Tintinalli's Emergency Medicine: A Comprehensive Study Guide. New York, NY: McGraw-Hill; 2011.
- Place R, Lagoc AT, Mayer TA, Lawlor CJ. Oncology and Hematology Emergencies in Children. In: Tintinalli JE, Stapczynski J, Ma O, Cline DM, Cydulka RK, Meckler GD, T. eds. Tintinalli's Emergency Medicine: A Comprehensive Study Guide. New York, NY: McGraw-Hill; 2011