Neonatal resuscitation: Difference between revisions

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#*IV dextrose at 1.5 maintenance
#*IV dextrose at 1.5 maintenance
#*Dialysis if ammonia >500
#*Dialysis if ammonia >500
===Empiric Treatment for Unstable Neonates===
{| class="wikitable"
| align="center" style="background:#f0f0f0;"|'''Medication/Intervention'''
| align="center" style="background:#f0f0f0;"|'''Indication'''
| align="center" style="background:#f0f0f0;"|'''Dose/Size (for neonate)'''
|-
| Glucose||[[Hypoglycemia]]||5–10 mL/kg of 10% dextrose in water IV
|-
| 3% normal saline||Symptomatic [[hyponatremia]]||3–5 mL/kg bolus IV
|-
| Calcium||[[Hypocalcemia]]||50–100 milligrams/kg calcium gluconate or 20 milligrams/kg calcium chloride IV
|-
| [[Cefotaxime]]||Infection||50 milligrams/kg IV
|-
| Ampicillin||Infection||50 milligrams/kg IV
|-
| Packed red blood cells||[[Anemia]]||10 mL/kg IV
|-
| Normal saline||Hypotension, dehydration||20 mL/kg IV
|-
| 10% dextrose in one fourth normal saline||Metabolic disease||1.5 maintenance (6 mL/kg/h for the first 10 kg)
|-
| Endotracheal intubation||Hypoventilation or frequent apnea||3mm for preemie; 3mm for term neonate, 4mm for older infant
|}


==See Also==
==See Also==

Revision as of 01:28, 9 May 2016

Use this note for the non-delivery related resuscitation of the newborn; see newborn resuscitation for immediate after-delivery resuscitation. See newborn critical care quick reference for vital signs and drug doses, and equipment sizes.

Background

Clinical Features

  • Neonate in shock
  • Neonate <1mo age

Differential Diagnosis

Sick Neonate

THE MISFITS [1]

Diagnosis

  1. Blood glucose (stat)
  2. Sepsis workup
  3. ECG
  4. Ammonia to rule in Inborn Errors^
    1. Need to look up values for neonate. Ammonia is high as liver is immature (i.e. that's why neonates are jaundice)

If hypoxic or evidence of CHF assume CHD

  • CHF in neonate = hepatomegaly, wheezing, gallop
  • if unclear do Hyperoxia test
    • place infant on 100% O2 for 10 minutes
    • check ABG, if O2<100 torr, highly predictive of CHD
    • some use Pulse Ox <95%, less sensitive
  • Abdominal xrays may help rule in intestinal disaster early

Management

  1. Full sepsis work-up
  2. Pressors if CHD suspected
  3. Intubate and give PGE
    • Sides effects of PGE include apnea (10%)
  4. If inborn errors suspected
    • IV dextrose at 1.5 maintenance
    • Dialysis if ammonia >500


Empiric Treatment for Unstable Neonates

Medication/Intervention Indication Dose/Size (for neonate)
Glucose Hypoglycemia 5–10 mL/kg of 10% dextrose in water IV
3% normal saline Symptomatic hyponatremia 3–5 mL/kg bolus IV
Calcium Hypocalcemia 50–100 milligrams/kg calcium gluconate or 20 milligrams/kg calcium chloride IV
Cefotaxime Infection 50 milligrams/kg IV
Ampicillin Infection 50 milligrams/kg IV
Packed red blood cells Anemia 10 mL/kg IV
Normal saline Hypotension, dehydration 20 mL/kg IV
10% dextrose in one fourth normal saline Metabolic disease 1.5 maintenance (6 mL/kg/h for the first 10 kg)
Endotracheal intubation Hypoventilation or frequent apnea 3mm for preemie; 3mm for term neonate, 4mm for older infant

See Also

External Links

Video

{{#widget:YouTube|id=B6jEgEexbEU}}

References

  1. Brousseau T, Sharieff GQ. Newborn emergencies: the first 30 days of life. Pediatr Clin North Am. 2006 Feb;53(1):69-84, vi.