Impetigo: Difference between revisions
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**Typical causative organisms are ''[[Staphylococcus aureus]] or [[Streptococcus pyogenes]]'' | **Typical causative organisms are ''[[Staphylococcus aureus]] or [[Streptococcus pyogenes]]'' | ||
*Fever and systemic signs are uncommon | *Fever and systemic signs are uncommon | ||
* | *[[Post-streptococcal glomerular nephritis]] is a possible complication | ||
==Diagnosis== | ==Diagnosis== | ||
Revision as of 05:51, 21 February 2016
Background
- Superficial epidermal infection characterized by amber crusts (nonbullous) or vesicles (bullous)
- May be super-infection or primary infection
- Typical causative organisms are Staphylococcus aureus or Streptococcus pyogenes
- Fever and systemic signs are uncommon
- Post-streptococcal glomerular nephritis is a possible complication
Diagnosis
- Nonbullous
- Erythematous macules/papules develop into vesicles which become pustular and rupture
- As rupture release yellow fluid which dries to form stratified golden crust
- Erythematous macules/papules develop into vesicles which become pustular and rupture
- Bullous
- Bullae form as result of staph toxin
- Some cases caused by MRSA
Work-up
- Clinical diagnosis
Differential Diagnosis
Other Rash
- Acute generalized exanthematous pustulosis
- Allergic reaction
- Aphthous stomatitis
- Atopic dermatitis
- Coxsackie
- Dermatitis herpetiformis
- Exfoliative erythroderma
- Impetigo
- Pellagra
- Pityriasis rosea
- Serum Sickness
- Tinea capitus
- Tinea corporis
- Vitiligo
Treatment
Antibiotics
Coverage for MSSA, MRSA, Group A Strep
Topical therapy
- Mupirocin (Bactroban) 2% ointment q8hrs x 5 days
- For nonbullous impetigo, topic antibiotics are as effective as oral antibiotics
Oral Therapy
- Cephalexin 500mg (6.25mg/kg) PO q6hrs for 10 days OR
- Amoxicillin/Clavulanate 875mg (12.5mg/kg) PO q12hrs daily x 10 days OR
- Clindamycin 450mg PO q8hrs daily (or 10mg/kg PO q6hrs) for 10 days OR
- Dicloxacillin 500mg (3mg/kg) PO q6hrs daily x 10 days