Local anesthetics: Difference between revisions
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==Background== | ==Background== | ||
*Am'''i'''des have two "i's" (pr'''i'''locaine, l'''i'''docaine, etc) | |||
*Esters have one "i" (tetracaine, procaine, benzocaine, etc) | |||
*Ester local anesthetics more likely to cause allergic reaction due to metabolite PABA<ref>GlobalRPH. Local Anesthetics (ester and amide-type). http://www.globalrph.com/local-anesthetics.htm.</ref> | |||
{{Maximum doses of anesthetic agents}} | {{Maximum doses of anesthetic agents}} | ||
Revision as of 16:21, 12 January 2016
Background
- Amides have two "i's" (prilocaine, lidocaine, etc)
- Esters have one "i" (tetracaine, procaine, benzocaine, etc)
- Ester local anesthetics more likely to cause allergic reaction due to metabolite PABA[1]
Maximum Doses of Anesthetic Agents
| Agent | Without Epinephrine | With Epinephrine | Duration | Notes |
| Lidocaine | 5 mg/kg (max 300mg) | 7 mg/kg (max 500mg) | 30-90 min |
|
| Mepivicaine | 7 mg/kg | 8 mg/kg | ||
| Bupivicaine | 2.5 mg/kg (max 175mg) | 3 mg/kg (max 225mg) | 6-8 hr |
|
| Ropivacaine | 3 mg/kg | |||
| Prilocaine | 6 mg/kg | |||
| Tetracaine | 1 mg/kg | 1.5 mg/kg | 3hrs (10hrs with epi) | |
| Procaine | 7 mg/kg | 10 mg/kg | 30min (90min with epi) |
See Also
- ↑ GlobalRPH. Local Anesthetics (ester and amide-type). http://www.globalrph.com/local-anesthetics.htm.