Oxycodone: Difference between revisions
| Line 9: | Line 9: | ||
==Pediatric Dosing== | ==Pediatric Dosing== | ||
Pain | ===General Pain=== | ||
*0.05-0.15 mg/kg PO q4-6h prn | *0.05-0.15 mg/kg PO q4-6h prn | ||
*Max: 5 mg/dose | |||
==Special Populations== | ==Special Populations== | ||
*[[Drug Ratings in Pregnancy|Pregnancy Rating]]: C | *[[Drug Ratings in Pregnancy|Pregnancy Rating]]: C | ||
Revision as of 04:04, 21 October 2015
General
- Type: opioid
- Dosage Forms: PO
- Common Trade Names: Roxicodone, Oxycontin
Adult Dosing
General Pain
- 5-15 mg PO q4-6h
Pediatric Dosing
General Pain
- 0.05-0.15 mg/kg PO q4-6h prn
- Max: 5 mg/dose
Special Populations
- Pregnancy Rating: C
- Lactation Risk Categories: possibly unsafe
- Renal Dosing
- Adult: CrCl < 60: decrease starting dose
- Pediatric: CrCl 10-50: decrease starting dose 25%, CrCL < 10: decrease dose 50%
- Hepatic Dosing
- Adult: not defined
- Pediatric: not defined
Contraindications
- Allergy to class/drug
Adverse Reactions
Serious
- Respiratory Depression
- Apnea
- syncope
- bradycardia
- Seizures
- anaphylaxis
Common
- Nausea
- Rash
- Headache
- Fatigue
- xerostomia
- constipation
- Tremor
- transaminitis
Pharmacology
- Half-life: 3.5-4 hour
- Metabolism: Liver
- Excretion: urine
- Mechanism of Action:binds to various opioid receptors