ACTH (cosyntropin) stimulation test: Difference between revisions
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*Cosyntropin | ==Background== | ||
*ACTH (cosyntropin) stimulation test measures how well the adrenal glands respond to adrenocorticotropic hormone (ACTH) | |||
*ACTH is a hormone produced in the pituitary gland that stimulates the adrenal glands to release a hormone called cortisol | |||
*Man-made form of ACTH is called cosyntropin | |||
==Test== | |||
*ACTH (Cosyntropin) | |||
#Before: Draw serum cortisol | #Before: Draw serum cortisol | ||
#Time 0: ^0.25mg IM/IV over 2min | #Time 0: ^0.25mg IM/IV over 2min | ||
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== Treatment == | == Treatment == | ||
*Then give either | |||
**[[Dexamethasone]] 6mg IV | |||
**OR | |||
**[[Hydrocortisone]] 100mg IV | |||
==See Also== | |||
*[[Adrenal crisis]] | |||
==References== | |||
[[Category:Endo]] | [[Category:Endo]] | ||
Revision as of 22:35, 17 May 2015
Background
- ACTH (cosyntropin) stimulation test measures how well the adrenal glands respond to adrenocorticotropic hormone (ACTH)
- ACTH is a hormone produced in the pituitary gland that stimulates the adrenal glands to release a hormone called cortisol
- Man-made form of ACTH is called cosyntropin
Test
- ACTH (Cosyntropin)
- Before: Draw serum cortisol
- Time 0: ^0.25mg IM/IV over 2min
- Time 30: Draw serum cortisol
- Time 60: Draw serum cortisol & give 100mg hydrodortison IVP
^0.125mg if <2yrs old
- Normal Response: Cortisol level doubles from baseline after Cosyntropin administration
- Adrenal Insufficiency: Cortisol level fails to rise after Cosyntropin administration
Treatment
- Then give either
- Dexamethasone 6mg IV
- OR
- Hydrocortisone 100mg IV