Myxoma: Difference between revisions

 
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==Background==
==Background==
[[File:Myxoma.jpg|thumb|A myxoma: a gelatinous tumor attached by a narrow pedicle to the atrial septum. The myxoma has an irregular surface and nearly fills the left atrium.]]
*Most common primary cardiac neoplasm
*Most common primary cardiac neoplasm
*~80% of myxomas originate in the left atrium, with the remainder in the right atrium<ref>Kuon E, Kreplin M, Weiss W, Dahm JB. The challenge presented by right atrial myxoma. Herz. 2004 Nov;29(7):702-9. doi: 10.1007/s00059-004-2571-7. PMID: 15580325.</ref>
*~80% of myxomas originate in the left atrium, with the remainder in the right atrium<ref>Kuon E, Kreplin M, Weiss W, Dahm JB. The challenge presented by right atrial myxoma. Herz. 2004 Nov;29(7):702-9. doi: 10.1007/s00059-004-2571-7. PMID: 15580325.</ref>
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==Evaluation==
==Evaluation==
[[File:PMC4582919 amjcaserep-16-645-g001.png|thumb|(A) Cardiac MRI showing atrial myxoma during systole. (B) Cardiac MRI showing atrial myxoma during diastole. RA – right atrium; RV – right ventricle; LA – left atrium; LV – left ventricle; arrow – myxoma.]]
[[File:PMC5412748 JCE-27-33-g007.png|thumb| Left atrial myxomas. (a) Parasternal long-axis view showing wedging of the myxoma into the mitral valve; (b) same case (four chamber view); (c) three-dimensional transesophageal echocardiography visualization of a left atrium myxoma attached to the posterior wall of the left atrium proximal to the pulmonary vein; (d) transesophageal echocardiography four chamber view of a large left atrium myxoma obstructing the mitral valve.]]
===Workup===
===Workup===
*Transthoracic echocardiogram
*Transesophageal echocardiogram
*Cardiac MRI


===Diagnosis===
===Diagnosis===
*Typical location of myxomas is typically amenable to visualization with TTE
*Typical location of myxomas is amenable to visualization with TTE


==Management==
==Management==
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==Disposition==
==Disposition==
 
*Most often admit for further management including potential anticoagulation and resection


==See Also==
==See Also==
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==References==
==References==
<references/>
<references/>
[[Category:Cardiology]]

Latest revision as of 01:44, 22 July 2024

Background

A myxoma: a gelatinous tumor attached by a narrow pedicle to the atrial septum. The myxoma has an irregular surface and nearly fills the left atrium.
  • Most common primary cardiac neoplasm
  • ~80% of myxomas originate in the left atrium, with the remainder in the right atrium[1]

Clinical Features

  • Cardiovascular symptoms mimicking mitral valve obstruction (e.g., left atrial hypertrophy)
  • Increased risk of systemic embolization
  • Constitutional symptoms (e.g., fever, weight loss)

Differential Diagnosis

Evaluation

(A) Cardiac MRI showing atrial myxoma during systole. (B) Cardiac MRI showing atrial myxoma during diastole. RA – right atrium; RV – right ventricle; LA – left atrium; LV – left ventricle; arrow – myxoma.
Left atrial myxomas. (a) Parasternal long-axis view showing wedging of the myxoma into the mitral valve; (b) same case (four chamber view); (c) three-dimensional transesophageal echocardiography visualization of a left atrium myxoma attached to the posterior wall of the left atrium proximal to the pulmonary vein; (d) transesophageal echocardiography four chamber view of a large left atrium myxoma obstructing the mitral valve.

Workup

  • Transthoracic echocardiogram
  • Transesophageal echocardiogram
  • Cardiac MRI

Diagnosis

  • Typical location of myxomas is amenable to visualization with TTE

Management

  • Once presumptive diagnosis made, prompt resection is required due to elevated risk of embolization or cardiac complications[2]

Disposition

  • Most often admit for further management including potential anticoagulation and resection

See Also

External Links

References

  1. Kuon E, Kreplin M, Weiss W, Dahm JB. The challenge presented by right atrial myxoma. Herz. 2004 Nov;29(7):702-9. doi: 10.1007/s00059-004-2571-7. PMID: 15580325.
  2. Keeling IM, Oberwalder P, Anelli-Monti M, Schuchlenz H, Demel U, Tilz GP, Rehak P, Rigler B. Cardiac myxomas: 24 years of experience in 49 patients. Eur J Cardiothorac Surg. 2002 Dec;22(6):971-7. doi: 10.1016/s1010-7940(02)00592-4. PMID: 12467822.