Anticonvulsants: Difference between revisions
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===Pediatric [[Anticonvulsants]] Table === | ===Pediatric [[Anticonvulsants]] Table === | ||
{| class="wikitable" | {| class="wikitable" | ||
! Drug !! Dose !! Infusion Rate !! Age !! Comments/Cautions | ! Drug !! Dose !! Infusion Rate (Minutes)!! Age !! Comments/Cautions | ||
|- | |- | ||
| [[Levetiracetam]] || | | [[Levetiracetam]] || | ||
*60 mg/kg/dose IV/IO | *60 mg/kg/dose IV/IO | ||
*MAX: 3000 mg/dose | *MAX: 3000 mg/dose | ||
|| | || ≥5 || Any || Most commonly used agent | ||
|- | |- | ||
| [[Fosphenytoin]] || | | [[Fosphenytoin]] || | ||
*20 mg phenytoin equivalent (PE)/kg/dose IV/IO/IM | *20 mg phenytoin equivalent (PE)/kg/dose IV/IO/IM | ||
*MAX: 1000 PE/dose | *MAX: 1000 PE/dose | ||
|| | || ≥10 || Any || Choose alternate drug if on phenytoin at home; may decrease BP/HR | ||
|- | |- | ||
| [[Valproic acid]] || | | [[Valproic acid]] || | ||
*40 mg/kg/dose IV/IO | *40 mg/kg/dose IV/IO | ||
*MAX: 3000 mg/dose | *MAX: 3000 mg/dose | ||
|| | || ≥10 || ≥2 years || Caution in patients with liver dysfunction, mitochondrial disease, urea disorder, thrombocytopenia, or unexplained developmental delay | ||
|- | |- | ||
| [[Phenytoin]] || | | [[Phenytoin]] || | ||
*20 mg/kg/dose IV/IO | *20 mg/kg/dose IV/IO | ||
*MAX: 1000 mg/dose | *MAX: 1000 mg/dose | ||
|| | || ≥20 || Any || Choose alternate drug if on phenytoin at home; may decrease BP/HR | ||
|- | |- | ||
| [[Phenobarbital]] || | | [[Phenobarbital]] || | ||
*20 mg/kg/dose IV/IO | *20 mg/kg/dose IV/IO | ||
*MAX: 1000 mg/dose | *MAX: 1000 mg/dose | ||
|| | || ≥20 || <6 months || Respiratory depression, especially in combination with benzos | ||
|} | |} | ||
Revision as of 20:43, 19 October 2022
- Carbamazepine (Tegretol)
- Clobazam (Onfi)
- Diazepam (Valium)
- Ethosuximide
- Fosphenytoin
- Gabapentin (Neurontin)
- Lacosamide (Vimpat)
- Lamotrigine (Lamictal)
- Levetiracetam (Keppra)
- Lorazepam (Ativan)
- Midazolam (Versed)
- Oxcarbazepine (Trileptal)
- Pentobarbital
- Phenobarbital
- Phenytoin (Dilantin)
- Propofol
- Topiramate (Topamax)
- Valproate (Depakote)
- Zonisamide
Pediatric Anticonvulsants Table
| Drug | Dose | Infusion Rate (Minutes) | Age | Comments/Cautions |
|---|---|---|---|---|
| Levetiracetam |
|
≥5 | Any | Most commonly used agent |
| Fosphenytoin |
|
≥10 | Any | Choose alternate drug if on phenytoin at home; may decrease BP/HR |
| Valproic acid |
|
≥10 | ≥2 years | Caution in patients with liver dysfunction, mitochondrial disease, urea disorder, thrombocytopenia, or unexplained developmental delay |
| Phenytoin |
|
≥20 | Any | Choose alternate drug if on phenytoin at home; may decrease BP/HR |
| Phenobarbital |
|
≥20 | <6 months | Respiratory depression, especially in combination with benzos |