Anticonvulsants: Difference between revisions

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*[[Valproate]] (Depakote)
*[[Valproate]] (Depakote)
*[[Zonisamide]]
*[[Zonisamide]]
{| class="wikitable"
! Drug !! Dose !! Infusion Rate !! Age !! Comments/Cautions
|-
| [[Levetiracetam]] || 60 mg/kg/dose IV/IO (MAX 3000 mg/dose) || Over 5 minutes || Any || Most commonly used agent
|-
| [[Fosphenytoin]] || 20 mg phenytoin equivalent (PE)/kg/dose IV/IO/IM (MAX 1000 PE/dose) || Over 10 minutes || Any || Choose alternate drug if on phytoin at home; may decrease BP/HR
|-
| [[Valproic acid]] || 40 mg/kg/dose IV/IO (MAX 3000 mg/dose) || Over 10 minutes || >2 years || Caution in patients with liver dysfunciton, mitochondrial disease, urea disorder, thrombocytopenia, or unexplained developmental delay
|-
| [[Phenytoin]] || 20 mg/kg/dose IV/IO (MAX 1000 mg/dose) || Over 20 minutes || Any || Choose alternate drug if on phytoin at home; may decrease BP/HR
|-
| [[Phenobarbital]] || 20 mg/kg/dose IV/IO (MAX 1000 mg/dose) || Over 20 minutes || <6 months || Repiratory depression, espeically in combination with benzos
|}


==See Also==
==See Also==

Revision as of 20:35, 19 October 2022

Drug Dose Infusion Rate Age Comments/Cautions
Levetiracetam 60 mg/kg/dose IV/IO (MAX 3000 mg/dose) Over 5 minutes Any Most commonly used agent
Fosphenytoin 20 mg phenytoin equivalent (PE)/kg/dose IV/IO/IM (MAX 1000 PE/dose) Over 10 minutes Any Choose alternate drug if on phytoin at home; may decrease BP/HR
Valproic acid 40 mg/kg/dose IV/IO (MAX 3000 mg/dose) Over 10 minutes >2 years Caution in patients with liver dysfunciton, mitochondrial disease, urea disorder, thrombocytopenia, or unexplained developmental delay
Phenytoin 20 mg/kg/dose IV/IO (MAX 1000 mg/dose) Over 20 minutes Any Choose alternate drug if on phytoin at home; may decrease BP/HR
Phenobarbital 20 mg/kg/dose IV/IO (MAX 1000 mg/dose) Over 20 minutes <6 months Repiratory depression, espeically in combination with benzos

See Also