Anticonvulsants: Difference between revisions
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*[[Valproate]] (Depakote) | *[[Valproate]] (Depakote) | ||
*[[Zonisamide]] | *[[Zonisamide]] | ||
{| class="wikitable" | |||
! Drug !! Dose !! Infusion Rate !! Age !! Comments/Cautions | |||
|- | |||
| [[Levetiracetam]] || 60 mg/kg/dose IV/IO (MAX 3000 mg/dose) || Over 5 minutes || Any || Most commonly used agent | |||
|- | |||
| [[Fosphenytoin]] || 20 mg phenytoin equivalent (PE)/kg/dose IV/IO/IM (MAX 1000 PE/dose) || Over 10 minutes || Any || Choose alternate drug if on phytoin at home; may decrease BP/HR | |||
|- | |||
| [[Valproic acid]] || 40 mg/kg/dose IV/IO (MAX 3000 mg/dose) || Over 10 minutes || >2 years || Caution in patients with liver dysfunciton, mitochondrial disease, urea disorder, thrombocytopenia, or unexplained developmental delay | |||
|- | |||
| [[Phenytoin]] || 20 mg/kg/dose IV/IO (MAX 1000 mg/dose) || Over 20 minutes || Any || Choose alternate drug if on phytoin at home; may decrease BP/HR | |||
|- | |||
| [[Phenobarbital]] || 20 mg/kg/dose IV/IO (MAX 1000 mg/dose) || Over 20 minutes || <6 months || Repiratory depression, espeically in combination with benzos | |||
|} | |||
==See Also== | ==See Also== | ||
Revision as of 20:35, 19 October 2022
- Carbamazepine (Tegretol)
- Clobazam (Onfi)
- Diazepam (Valium)
- Ethosuximide
- Fosphenytoin
- Gabapentin (Neurontin)
- Lacosamide (Vimpat)
- Lamotrigine (Lamictal)
- Levetiracetam (Keppra)
- Lorazepam (Ativan)
- Midazolam (Versed)
- Oxcarbazepine (Trileptal)
- Pentobarbital
- Phenobarbital
- Phenytoin (Dilantin)
- Propofol
- Topiramate (Topamax)
- Valproate (Depakote)
- Zonisamide
| Drug | Dose | Infusion Rate | Age | Comments/Cautions |
|---|---|---|---|---|
| Levetiracetam | 60 mg/kg/dose IV/IO (MAX 3000 mg/dose) | Over 5 minutes | Any | Most commonly used agent |
| Fosphenytoin | 20 mg phenytoin equivalent (PE)/kg/dose IV/IO/IM (MAX 1000 PE/dose) | Over 10 minutes | Any | Choose alternate drug if on phytoin at home; may decrease BP/HR |
| Valproic acid | 40 mg/kg/dose IV/IO (MAX 3000 mg/dose) | Over 10 minutes | >2 years | Caution in patients with liver dysfunciton, mitochondrial disease, urea disorder, thrombocytopenia, or unexplained developmental delay |
| Phenytoin | 20 mg/kg/dose IV/IO (MAX 1000 mg/dose) | Over 20 minutes | Any | Choose alternate drug if on phytoin at home; may decrease BP/HR |
| Phenobarbital | 20 mg/kg/dose IV/IO (MAX 1000 mg/dose) | Over 20 minutes | <6 months | Repiratory depression, espeically in combination with benzos |
