Valacyclovir: Difference between revisions
(contraindication) |
(side effects) |
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==Adverse Reactions== | ==Adverse Reactions== | ||
===Serious=== | ===Serious=== | ||
*acute renal failure | |||
*thrombocytopenia | |||
*aplastic anemia | |||
*delirium | |||
*psychosis | |||
*seizures | |||
===Common=== | ===Common=== | ||
*nausea/vomiting | |||
*headache | |||
*abdominal pain | |||
*depression | |||
* elevated LFT's | |||
* fatigue | |||
==Pharmacology== | ==Pharmacology== | ||
Revision as of 21:30, 2 April 2015
General
- Type: inhibits DNA polymerase
- Dosage Forms: 500, 1000
- Common Trade Names: Valtrex
Adult Dosing
HSV-1
- Acute episode: 2000 mg PO BID x 1 day
- Suppression: 500 mg PO Qday
Genital HSV
- 1st episode: 1000 mg PO BID x 7-10 days, start within 48-72 hour of symptoms
- recurrence: 500 mg PO BID x 3 days, alternative: 1000 mg PO qday x 5 days
Shingles
- 1000 mg PO TID x 7 days
Pediatric Dosing
Genital HSV
- same as adult dosing for adolescents
Special Populations
- Pregnancy Rating:
- Lactation:
- Renal Dosing
- Adult
- Pediatric
- Hepatic Dosing
- Adult
- Pediatric
Contraindications
- Allergy to class/drug
- caution if renal impairment
Adverse Reactions
Serious
- acute renal failure
- thrombocytopenia
- aplastic anemia
- delirium
- psychosis
- seizures
Common
- nausea/vomiting
- headache
- abdominal pain
- depression
- elevated LFT's
- fatigue
Pharmacology
- Half-life:
- Metabolism:
- Excretion:
- Mechanism of Action: