Hydrocodone: Difference between revisions
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==General== | ==General== | ||
*Type: | *Type: [[Opioid]] | ||
*Dosage Forms: PO | *Dosage Forms: PO | ||
*Common Trade Names: Zohydro, Hysingla | *Common Trade Names: Zohydro, Hysingla | ||
*Commonly combined with [[acetaminophen]] as Norco and Vicodin | |||
==Adult Dosing== | ==Adult Dosing== | ||
===General=== | ===General=== | ||
For Pain, severe chronic | *For Pain, severe chronic: Individualize dose PO q12h; start 10mg PO q12h, may increase by 10mg PO q12h q3-7 days. Titrate slowly in elderly patients. | ||
==Pediatric Dosing== | ==Pediatric Dosing== | ||
Currently not recommended | *Currently not recommended | ||
==Special Populations== | ==Special Populations== | ||
| Line 24: | Line 24: | ||
==Contraindications== | ==Contraindications== | ||
*Allergy to class/drug | *Allergy to class/drug | ||
* labor and delivery | *labor and delivery | ||
* GI obstruction | *GI obstruction | ||
*paralytic ileus | *paralytic ileus | ||
* acute asthma exacerbation | *acute asthma exacerbation | ||
==Adverse Reactions== | ==Adverse Reactions== | ||
===Serious=== | ===Serious=== | ||
* respiratory depression | *respiratory depression | ||
*apnea | *apnea | ||
* hypotension, severe | *hypotension, severe | ||
*paralytic ileus | *paralytic ileus | ||
*bradycardia | *bradycardia | ||
* anaphylaxis | *anaphylaxis | ||
===Common=== | ===Common=== | ||
| Line 46: | Line 46: | ||
*headache | *headache | ||
*URI | *URI | ||
* tremor | *tremor | ||
==Pharmacology== | ==Pharmacology== | ||
Latest revision as of 01:44, 21 February 2021
General
- Type: Opioid
- Dosage Forms: PO
- Common Trade Names: Zohydro, Hysingla
- Commonly combined with acetaminophen as Norco and Vicodin
Adult Dosing
General
- For Pain, severe chronic: Individualize dose PO q12h; start 10mg PO q12h, may increase by 10mg PO q12h q3-7 days. Titrate slowly in elderly patients.
Pediatric Dosing
- Currently not recommended
Special Populations
- Pregnancy Rating: C
- Lactation Risk Categories: possibly unsafe
- Renal Dosing
- Adult: none
- Pediatric: none
- Hepatic Dosing
- Adult: not defined
- Pediatric: not defined
Contraindications
- Allergy to class/drug
- labor and delivery
- GI obstruction
- paralytic ileus
- acute asthma exacerbation
Adverse Reactions
Serious
- respiratory depression
- apnea
- hypotension, severe
- paralytic ileus
- bradycardia
- anaphylaxis
Common
- Constipation
- nausea
- fatigue
- vomiting
- xerostomia
- headache
- URI
- tremor
Pharmacology
- Half-life: 8 hour
- Metabolism: Liver
- Excretion: urine
- Mechanism of Action: bind to various opioid receptors