Duodenal atresia: Difference between revisions

 
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*Abdominal distention and bilious [[vomiting|emesis]] within first 24 hours of birth
*Abdominal distention and bilious [[vomiting|emesis]] within first 24 hours of birth
**Abdomen often markedly distended, with visible or palpable loops of bowel
**Abdomen often markedly distended, with visible or palpable loops of bowel
**NG tube aspirate >20 mL
**[[NG tube]] aspirate >20 mL
*Signs of [[dehydration (peds)|dehydration]] (e.g. dry mucous membranes, poor skin turgor, and sunken fontanelle)
*Signs of [[dehydration (peds)|dehydration]] (e.g. dry mucous membranes, poor skin turgor, and sunken fontanelle)
*+/- Signs of other congenital anomalies
*+/- Signs of other congenital anomalies
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==Evaluation==
==Evaluation==
[[File:DuodenalAtresiaXR.png|thumb|Double Bubble sign]]
*Imaging
*Imaging
**AP, lateral, and cross table XR should be obtained on all infants with concern for obstruction
**AP, lateral, and cross table [[KUB|XR]] should be obtained on all infants with concern for obstruction
**Classic double bubble sign due to dilation of the stomach and proximal duodenum
**Classic double bubble sign due to dilation of the stomach and proximal duodenum
**Absent distal gas
**Absent distal gas
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==Management==
==Management==
*NPO
*NPO
*NG tube to suction
*[[NG tube]] to suction
*Correct fluid and [[electrolyte abnormalities]]
*Correct [[IVF|fluid]] and [[electrolyte abnormalities]]
*[[Ampicillin]] and [[gentamicin]] (to prevent post-op infection)
*[[Ampicillin]] and [[gentamicin]] (to prevent post-op infection)
*Surgery
*Surgery
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[[Category:GI]]
[[Category:GI]]
[[Category:Pediatrics]]
[[Category:Pediatrics]]
[[Category:Surgery]]

Latest revision as of 16:30, 28 October 2019

Background

  • During weeks 6 and 7 of gestation, the GI tract becomes occluded then recanalizes during weeks 8 to 10
  • Duodenal atresia is thought to result from failure of recanalization
  • Often associated with other malformations such as biliary atresia or gallbladder agenesis
  • May also be associated with cardiac, renal, or vertebral abnormalities
  • About a quarter of patients born with duodenal atresia have Down syndrome

Clinical Features

Presentation is very early in the postnatal period

  • Abdominal distention and bilious emesis within first 24 hours of birth
    • Abdomen often markedly distended, with visible or palpable loops of bowel
    • NG tube aspirate >20 mL
  • Signs of dehydration (e.g. dry mucous membranes, poor skin turgor, and sunken fontanelle)
  • +/- Signs of other congenital anomalies

Differential Diagnosis

Nausea and vomiting (newborn)

Newborn '
Obstructive intestinal anomalies
Neurologic
Renal
Infectious
Metabolic/endocrine
Miscellaneous

Evaluation

Double Bubble sign
  • Imaging
    • AP, lateral, and cross table XR should be obtained on all infants with concern for obstruction
    • Classic double bubble sign due to dilation of the stomach and proximal duodenum
    • Absent distal gas

Management

Disposition

  • Admission

References