Hydrocodone: Difference between revisions
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==Adult Dosing== | ==Adult Dosing== | ||
===General=== | ===General=== | ||
For Pain, severe chronic | *For Pain, severe chronic: Individualize dose PO q12h; start 10mg PO q12h, may increase by 10mg PO q12h q3-7 days. Titrate slowly in elderly patients. | ||
==Pediatric Dosing== | ==Pediatric Dosing== | ||
Currently not recommended | *Currently not recommended | ||
==Special Populations== | ==Special Populations== | ||
Revision as of 20:23, 22 September 2019
General
- Type: opioid
- Dosage Forms: PO
- Common Trade Names: Zohydro, Hysingla
Adult Dosing
General
- For Pain, severe chronic: Individualize dose PO q12h; start 10mg PO q12h, may increase by 10mg PO q12h q3-7 days. Titrate slowly in elderly patients.
Pediatric Dosing
- Currently not recommended
Special Populations
- Pregnancy Rating: C
- Lactation Risk Categories: possibly unsafe
- Renal Dosing
- Adult: none
- Pediatric: none
- Hepatic Dosing
- Adult: not defined
- Pediatric: not defined
Contraindications
- Allergy to class/drug
- labor and delivery
- GI obstruction
- paralytic ileus
- acute asthma exacerbation
Adverse Reactions
Serious
- respiratory depression
- apnea
- hypotension, severe
- paralytic ileus
- bradycardia
- anaphylaxis
Common
- Constipation
- nausea
- fatigue
- vomiting
- xerostomia
- headache
- URI
- tremor
Pharmacology
- Half-life: 8 hour
- Metabolism: Liver
- Excretion: urine
- Mechanism of Action: bind to various opioid receptors