Pantoprazole: Difference between revisions
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*[[Drug Ratings in Pregnancy|Pregnancy Rating]]: | *[[Drug Ratings in Pregnancy|Pregnancy Rating]]: | ||
*Lactation: | *Lactation: | ||
** Pantoprazole is present in breast milk | |||
*Renal Dosing | *Renal Dosing | ||
**Adult | **Adult | ||
*** No adjustment necessary | |||
**Pediatric | **Pediatric | ||
*** Not defined | |||
*Hepatic Dosing | *Hepatic Dosing | ||
**Adult | **Adult | ||
*** No adjustment necessary | |||
**Pediatric | **Pediatric | ||
*** Not defined | |||
==Contraindications== | ==Contraindications== | ||
Revision as of 19:12, 2 April 2019
General
- Type: Proton-pump inhibitor
- Dosage Forms:
- Common Trade Names: Protonix, Somac, Forppi, Pantoloc, Pantozol, Pantomed, Zurcal, Zentro, Pan, Controloc, Tecta
Adult Dosing
Upper gastrointestinal bleeding
- 80mg x 1; then 8mg/hr
Pediatric Dosing
Special Populations
- Pregnancy Rating:
- Lactation:
- Pantoprazole is present in breast milk
- Renal Dosing
- Adult
- No adjustment necessary
- Pediatric
- Not defined
- Adult
- Hepatic Dosing
- Adult
- No adjustment necessary
- Pediatric
- Not defined
- Adult
Contraindications
- Allergy to class/drug
Adverse Reactions
Serious
- anaphylaxis
- SJS/TEN
- Renal impairment
- pancreatitis
- hepatic impairment
Common
- Headache
- abdominal pain
- nausea/vomiting/diarrhea
- AST/ALT elevation
Pharmacology
- Half-life: 1 hour
- Metabolism: Hepatic - CYP450
- Excretion: Urine/Feces
- Mechanism of Action: inhibits gastric parietal cell H+/K+ ATPase