Oxalic acid toxicity: Difference between revisions
m (Rossdonaldson1 moved page Oxalic acid to Oxalic acid toxicity) |
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*Also found in some species of plants | *Also found in some species of plants | ||
==Mechanism of Toxicity== | ===Mechanism of Toxicity=== | ||
*Solution form: | *Solution form: | ||
**Irritative and Corrosive | **Irritative and Corrosive | ||
**Causes hypocalcemia and formation of calcium oxalate crystals that can deposit in brain, heart, and kidneys. | **Causes [[hypocalcemia]] and formation of calcium oxalate crystals that can deposit in brain, heart, and kidneys. | ||
*Insoluble form: | *Insoluble form: | ||
**Local mucous membrane irritation | **Local mucous membrane irritation | ||
==Toxic Dose== | ===Toxic Dose=== | ||
*5-15 g can be lethal | *5-15 g can be lethal | ||
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**Skin and eye irritation and burning | **Skin and eye irritation and burning | ||
*Inhalation | *Inhalation | ||
**Sore throat, cough, wheezing, pulmonary edema | **[[Sore throat]], [[cough]], [[wheezing]], [[pulmonary edema]] | ||
*Ingestion | *Ingestion | ||
**Weakness, tetany, cardiac arrest | **[[Weakness]], tetany, [[cardiac arrest]] | ||
==Diagnosis== | ==Differential Diagnosis== | ||
==Evaluation== | |||
*Clinical | *Clinical | ||
*No specific levels for oxalic acid | *No specific levels for oxalic acid | ||
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*Protect the airway | *Protect the airway | ||
*Decontamination | *Decontamination | ||
*Calcium chloride or calcium gluconate to reverse hypocalcemia | *[[Calcium chloride]] or [[calcium gluconate]] to reverse hypocalcemia | ||
==Disposition== | |||
==References== | ==References== | ||
Latest revision as of 20:06, 1 February 2019
Background
- Used in bleach and rust removers
- Also found in some species of plants
Mechanism of Toxicity
- Solution form:
- Irritative and Corrosive
- Causes hypocalcemia and formation of calcium oxalate crystals that can deposit in brain, heart, and kidneys.
- Insoluble form:
- Local mucous membrane irritation
Toxic Dose
- 5-15 g can be lethal
Clinical Features
- Direct contact with skin/eyes
- Skin and eye irritation and burning
- Inhalation
- Ingestion
- Weakness, tetany, cardiac arrest
Differential Diagnosis
Evaluation
- Clinical
- No specific levels for oxalic acid
Management
- Protect the airway
- Decontamination
- Calcium chloride or calcium gluconate to reverse hypocalcemia
Disposition
References
- Olson, K. Poisoning and Drug Overdose, 1999.