Central cord syndrome: Difference between revisions

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==Clinical Features==
==Clinical Features==
*Quadriparesis (characteristically with worse function in the UL than in the LL)
*Quadriparesis (characteristically with worse function in the UL than in the LL)
*Possible loss of pain and temperature sensation, also greater in upper extremities
*Rare loss of pain and temperature sensation, also greater in upper extremities
*in contrast to anterior cord syndrome - an incomplete spinal cord injury affecting the blood supply to the anterior spinal structures. Symptoms include bilateral loss of pain and temperature (via spinothalamic tracts), bilateral weakness or paralysis below the lesion (via corticospinal tracts) and loss of sphincter control.


==Differential Diagnosis==
==Differential Diagnosis==

Revision as of 02:07, 21 January 2019

Background

Spinal cord tracts
  • Most common incomplete spinal cord injury

Etiology

  • Hyperextension injury of cervical spine
  • Disruption of blood flow to the spinal cord
  • Cervical spinal stenosis
  • Typically elderly patient with significant DJD (ligamentum flavum compresses cord, causing contusion to central portion of spinal cord)
  • Syringomyelia (progressive, chronic, pain/temperature loss first)
  • Central canal ependymoma

Clinical Features

  • Quadriparesis (characteristically with worse function in the UL than in the LL)
  • Rare loss of pain and temperature sensation, also greater in upper extremities
  • in contrast to anterior cord syndrome - an incomplete spinal cord injury affecting the blood supply to the anterior spinal structures. Symptoms include bilateral loss of pain and temperature (via spinothalamic tracts), bilateral weakness or paralysis below the lesion (via corticospinal tracts) and loss of sphincter control.

Differential Diagnosis

Spinal Cord Syndromes

Evaluation

  • MRI for direct evidence for impingement
  • CT may show central canal stenosis with indirect estimation of impingement

Management

Acute Management of Spinal Cord Injury

  • Neurogenic shock management
  • Consider intubation injuries at C5 or above
    • Manual in-line stabilization reduces cervical movement better than C-collar, but be careful of tracheal pressures inadvertently applied which can worsen laryngeal visualization[1][2]
    • Direct laryngoscopy causes C-spine extension at atlanto-occipital junction, C1-C2, and C4-C7 in order from most to least
    • Consider video laryngoscopy with hyperangulated stylet or bougie assisted DL to intubate higher-grade laryngoscopy views of vocal cords without C-spine overextension[3]
    • Post-intubation sedation takes into consideration hemodynamics and potential intraoperative EMG and evoked potential monitoring by anesthesia
  • Consider surgical intervention for:
  • Steroids are no longer recommended
    • Administration of methylprednisolone (MP) for the treatment of acute spinal cord injury (SCI) is not recommended. Clinicians considering MP therapy should bear in mind that the drug is NOT approved by the FDA for this indication. There is no Class I or Class II medical evidence supporting the clinical benefit of MP in the treatment of acute SCI. Scattered reports of Class III evidence claim inconsistent effects likely related to random chance or selection bias. However, Class I, II, and III evidence exists that high-dose steroids are associated with harmful side effects including death.[6]
    • See EBQ:High Dose Steroids in Cord Injury for further discussion

Disposition

  • Admission for acute injury
  • Surgery within 24 hours is safe and effective, but may be extended to < 2 weeks after injury[7]

External Links

See Also

References

  1. The effect of laryngoscopy of different cervical spine immobilisation techniques. Heath KJ. Anaesthesia. 1994 Oct; 49(10):843-5.
  2. Manual in-line stabilization increases pressures applied by the laryngoscope blade during direct laryngoscopy and orotracheal intubation. Santoni BG, Hindman BJ, Puttlitz CM, Weeks JB, Johnson N, Maktabi MA, Todd MM. Anesthesiology. 2009 Jan; 110(1):24-31.
  3. Cervical spinal motion during intubation: efficacy of stabilization maneuvers in the setting of complete segmental instability. Lennarson PJ, Smith DW, Sawin PD, Todd MM, Sato Y, Traynelis VC. J Neurosurg. 2001 Apr; 94(2 Suppl):265-70.
  4. Improvement of motor-evoked potentials by ketamine and spatial facilitation during spinal surgery in a young child. Erb TO, Ryhult SE, Duitmann E, Hasler C, Luetschg J, Frei FJ. Anesth Analg. 2005 Jun; 100(6):1634-6.
  5. Effects of dexmedetomidine on intraoperative motor and somatosensory evoked potential monitoring during spinal surgery in adolescents. Tobias JD, Goble TJ, Bates G, Anderson JT, Hoernschemeyer DG. Paediatr Anaesth. 2008 Nov; 18(11):1082-8.
  6. Hurlbert RJ et al. Pharmacological therapy for acute spinal cord injury. Neurosurgery. 2013 Mar;72 Suppl 2:93-105 http://www.ncbi.nlm.nih.gov/pubmed/23417182
  7. Anderson KK et al. Optimal Timing of Surgical Decompression for Acute Traumatic Central Cord Syndrome: A Systematic Review of the Literature. Neurosurgery. 2015 Oct;77 Suppl 4:S15-32.