View source for Mebendazole

==Administration==
*Type: [[Antiparasitic]] (used to treat nematodes)
*Dosage Forms: Tablet 100mg
*Routes of Administration: Oral
*Common Trade Names: Emverm

==Adult Dosing==
*100mg PO BID x 3 days


===Indications by Disease===
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==Pediatric Dosing==
≥2yo: 100mg PO BID x 3 days


===Indications by Disease===
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==Special Populations==
*[[Drug Ratings in Pregnancy|Pregnancy Rating]]: C
*[[Lactation risk categories|Lactation risk]]: infant risk cannot be ruled out
*Renal dosing: no adjustment
*Hepatic impairment: may need dose reduction

==Contraindications==
*Allergy to class/drug

==Adverse Reactions==
===Serious===
*Agranulocytosis
*Hepatitis
*Seizure
*Angioedema
===Common===
*Abdominal pain, diarrhea

==Pharmacology==
*Half-life: 0.8-11.5h
*Metabolism: Hepatic
*Excretion: Fecal

==Mechanism of Action==
*Causes parasitic microtubules to degenerate, inhibiting glucose uptake and glycogen storage

==Comments==

==See Also==
*[[Parasites]]
*[[Travel medicine]]
==References==
<references/>
[[Category:Pharmacology]]
[[Category:ID]]