View source for Hemostatic agents

==Types==
{| class="wikitable"
| align="center" style="background:#f0f0f0;"|'''Plant-Based'''
| align="center" style="background:#f0f0f0;"|'''Oxidized cellulose (OC) and oxidized regenerated cellulose (ORC)'''
|-
| Gelatin-based||Purified pork or bovine skin; absorbs 45 times its weight of its initial volume causing hemostasis. Excessive swelling can lead to nerve compression
|-
| Collagen-based||Derived from tissue; shows cell compatibility, adhesion, growth and migration.
|-
| Fibrin-based||High concentrations of fibrinogen, thrombin and additional components (clotting factors)
|-
| Thrombin-based||Directly participate in the coagulation cascade process that promotes and modulates coagulation. Provides a lattice for platelet aggregation and thrombus formation.
|-
| Chitin-based||Polysaccharide biopolymer produced naturally by algae through fermentation. Also known as chitosan in its deacetylated form. Chitosan has been shown to be more effective that chitin in controlling severe hemorrhage.
|}

===Characteristics<ref>Kheirabadi B. "Evaluation of Topical Hemostatic Agents for Combat Wound Treatment." The Army Medical Department Journal. April – June 2011. Pages 25-31</ref>===
{| class="wikitable"
| align="center" style="background:#f0f0f0;"|'''Charateristic'''
| align="center" style="background:#f0f0f0;"|'''QuikClot ACS+'''
| align="center" style="background:#f0f0f0;"|'''HemCon'''
| align="center" style="background:#f0f0f0;"|'''Celox'''
| align="center" style="background:#f0f0f0;"|'''WoundSat'''
| align="center" style="background:#f0f0f0;"|'''Combat Gauze'''
|-
| Hemostatic efficacy||+||+||+++||++++||++++
|-
| Side effects||No||No ||No||Yes||No
|-
| Ready to use||Yes||Yes||Yes||Yes||Yes
|-
| Training requirement||+||+||+||+++||++
|-
| Lightweight, durable||+||+++||+++||+||+++
|-
| 2-year shelf life||Yes||Yes||Yes||Yes||Yes
|-
| Stable in extreme conditions||Yes||Yes||Yes||Yes||Yes
|-
| Cleared by FDA||Yes||Yes||Yes||Yes||Yes
|-
| Biodegradable||No||No ||Yes||No||No
|-
| Cost ($)||~30||~75||~25||~30||~25
|}

==Use==
*For compressible hemorrhage not amenable to [[tourniquet]] use or as an adjunct to [[tourniquet]] removal (if evacuation time is anticipated to be longer than two hours), use Combat Gauze
*Celox Gauze and ChitoGauze may also be used if Combat Gauze is not available. 
*Hemostatic dressings should be applied with at least 3 minutes of direct pressure.

==See Also==
*[[Bleeding treatments]]
*[[Tactical combat casualty care]]

==References==
<references/>

[[Category:Trauma]]
[[Category:EMS]]
[[Category:Military]]