View source for Anion gap

==Elevated Anion Gap==
===DDx===
MUDPILES
*M - Methanol
*U - Uremia
*D - DKA
*P - Paraldehyde
*I - Iron, INH
*L - Lactic acidosis
*E - Ethylene glycol
*S - Salicylates

Also:
*Starvation/ETOH ketoacidosis
*CO, CN poisoning (incr. lactate)

==Low Anion Gap==
===Background===
*< 7 meq/L

===DDX===
*Lab error
*Decreased "unmeasured" anions
**hypoalbuminemia
*Increased "unmeasured" cations
**[[Hyperkalemia]]
**[[Hypercalcemia]]
**[[Hypermagnesemia]]
**[[Lithium Toxicity]]
*Increased cationic paraprotein
**Multiple myeloma
**Polyclonal IgG gammopathy
*Pseudo
**Severe [[Hypernatremia]] (>170 meq/L)
***True conc of Na is underestimated
**Marked hyperlipidemia
***Leads to overestimation of plasma Cl conc)
**Bromide intoxication (e.g. for myasthenia gravis and some herbal medications)
***Machine mistakenly reads Br as Cl

*AG falls by 2.5 meq/L for every 1 g/dL reduction in albumin concentration


==See Also==
[[Anion Gap and Osmolar Gap (High)]]

==Source==
Kaji Questions <br />
MISTRY 6/06

[[Category:FEN]]
[[Category:Tox]]