Brown-Séquard syndrome

(Redirected from Brown-Sequard syndrome)


Spinal cord tracts
  • Transverse hemisection of spinal cord
  • Unilateral cord compression

Clinical Features

  • Decussation of corticospinal tract at the medulla and complete lack of decussation of fibers of the posterior columns result in:
    • Ipsilateral spastic paresis
    • Ipsilateral loss of proprioception, vibration
  • Decussation of anterolateral fibers within spinal tract one level up via anterior white commissure results in:
    • Contralateral loss of pain, temperature (ie 'sensory dissociation')

Differential Diagnosis

Spinal Cord Syndromes


  • Clinical presentation and mechanism


  • Consider intubation injuries at C5 or above
  • Consider surgical intervention for:
  • Steroids are no longer recommended
    • Administration of methylprednisolone (MP) for the treatment of acute spinal cord injury (SCI) is not recommended. Clinicians considering MP therapy should bear in mind that the drug is not Food and Drug Administration (FDA) approved for this application. There is no Class I or Class II medical evidence supporting the clinical benefit of MP in the treatment of acute SCI. Scattered reports of Class III evidence claim inconsistent effects likely related to random chance or selection bias. However, Class I, II, and III evidence exists that high-dose steroids are associated with harmful side effects including death.[1]
    • See EBQ:High Dose Steroids in Cord Injury for further discussion


  • Good


  • Admission

See Also

External Links


  1. Hurlbert RJ et al. Pharmacological therapy for acute spinal cord injury. Neurosurgery. 2013 Mar;72 Suppl 2:93-105