Anaerobic bacteria
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Background
- Origin - gut, mouth, head/neck (50% of chronic sinusitis), lung, female gu tract
- Cant grow unless culture specifically asked. 3% of bacteremia, <1% of cystitis
Organisms
- Bacteroides (GNR)
- Peptostreptococus (GPC)
- P. Acnes (GPR)
- Clostridium (GPR)
Anerobic Antibiogram
Category | Organism | Actinomyces | Bacteroides fragilis | Prevotella melaninogenica | Clostridium difficile | Clostridium (not difficile) | Fusobacterium necrophorum | Peptostreptococcus sp. |
Penicillins | Penicillin G | S | R | S | X2 | S | I | S |
Penicillin V | I | I | R | X1 | S | I | S | |
Anti-Staphylocccal Penicillins | Methicillin | R | R | R | X1 | X1 | X1 | S |
Nafcillin/Oxacillin | R | R | R | X1 | X1 | X1 | S | |
Cloxacillin/Diclox. | R | R | R | X1 | X1 | X1 | S | |
Amino-Penicillins | AMP/Amox | S | R | S | X1 | S | S | S |
Amox-Clav | S | S | S | X1 | S | S | S | |
AMP-Sulb | S | S | S | X2 | S | S | S | |
Anti-Pseudomonal Penicillins | Ticarcillin | X1 | R | S | X1 | S | X1 | S |
Ticar-Clav | X1 | S | S | X1 | S | S | S | |
Pip-Tazo | X1 | S | S | X1 | S | S | S | |
Piperacillin | S | R | S | X2 | S | X1 | S | |
Carbapenems | Doripenem | X1 | S | S | X2 | S | S | S |
Ertapenem | S | S | S | X2 | S | S | S | |
Imipenem | S | S | S | X2 | S | S | S | |
Meropenem | X1 | S | S | X2 | S | S | S | |
Aztreonam | R | R | R | R | R | X1 | R | |
Fluroquinolones | Ciprofloxacin | R | R | R | R | I | X1 | I |
Ofloxacin | I | R | I | X1 | I | X1 | I | |
Pefloxacin | X1 | R | X1 | X1 | X1 | X1 | X1 | |
Levofloxacin | X1 | R | S | R | S | X1 | S | |
Moxifloxacin | S | I | S | R | I | I | S | |
Gemifloxacin | X1 | R | X1 | X1 | X1 | X1 | X1 | |
Gatifloxacin | S | I | S | R | S | X1 | S | |
1st G Cephalo | Cefazolin | X1 | R | X1 | X1 | X1 | X1 | X1 |
2nd G. Cephalo | Cefotetan | X1 | I | S | X1 | S | X1 | S |
Cefoxitin | X1 | S | S | R | S | S | S | |
Cefuroxime | X1 | R | S | X1 | S | X1 | S | |
3rd/4th G. Cephalo | Cefotaxime | X1 | R | S | R | S | X1 | S |
Cefizoxime | S | I | S | R | S | X1 | S | |
CefTRIAXone | S | R | I | X1 | S | X1 | S | |
Ceftaroline | X1 | R | X1 | X1 | X1 | X1 | X1 | |
CefTAZidime | X1 | R | S | X1 | S | X1 | S | |
Cefepime | X1 | R | R | R | X1 | X1 | S | |
Oral 1st G. Cephalo | Cefadroxil | X1 | X1 | X1 | X1 | X1 | X1 | X1 |
Cephalexin | X1 | R | X1 | X1 | X1 | X1 | S | |
Oral 2nd G. Cephalo | Cefaclor/Loracarbef | X1 | R | S | X1 | X1 | X1 | S |
Cefproxil | X1 | R | S | X1 | S | X1 | S | |
Cefuroxime axetil | X1 | R | S | X1 | S | X1 | S | |
Oral 3rd G. Cephalo | Cefixime | X1 | R | S | X1 | R | X1 | S |
Ceftibuten | X1 | R | X1 | X1 | X1 | X1 | X1 | |
Cefpodox/Cefdinir/Cefditoren | X1 | X1 | X1 | X1 | X1 | X1 | X1 | |
Aminoglycosides | Gentamicin | R | R | R | R | X1 | R | R |
Tobramycin | R | R | R | R | X1 | R | R | |
Amikacin | R | R | R | R | X1 | R | R | |
Chloramphenicol | X2 | X2 | S | I | S | S | S | |
Clindamycin | S | I | S | X1 | I | S | S | |
Macrolides | Erythromycin | S | R | X1 | X1 | I | R | I |
Azithromycin | S | R | S | X1 | S | R | S | |
Clarithromycin | S | R | S | X1 | S | R | I | |
Ketolide | Telithromycin | X1 | X1 | X1 | X1 | X1 | X1 | S |
Tetracyclines | Doxycycline | S | I | S | X1 | S | X1 | S |
Minocycline | S | I | S | X1 | S | X1 | S | |
Glycylcycline | Tigecycline | X1 | S | S | X1 | S | S | S |
Daptomycin | X1 | X1 | X1 | X1 | X1 | X1 | X1 | |
Glyco/Lipoclycopeptides | Vancomycin | S | R | R | S | S | X1 | S |
Teicoplanin | X1 | X1 | X1 | S | S | X1 | S | |
Telavancin | S | R | R | S | S | X1 | S | |
Fusidic Acid | S | X1 | S | X1 | S | X1 | S | |
Trimethoprim | X1 | X2 | X1 | X1 | X1 | X1 | X1 | |
TMP-SMX | X1 | R | X1 | X1 | X1 | X1 | X1 | |
Urinary Agents | Nitrofurantoin | X1 | X1 | X1 | X1 | X1 | X1 | X1 |
Fosfomycin | X1 | X1 | X1 | X1 | X1 | X1 | X1 | |
Other | Rifampin | X1 | X1 | X1 | X1 | X1 | X1 | X1 |
Metronidazole | R | S | S | S | S+ | S | I | |
Quinupristin dalfoppristin | X1 | X1 | S | I | X2 | X1 | X1 | |
Linezolid | X1 | I | X1 | I | X2 | X1 | S | |
Colistimethate | X1 | X1 | X1 | X1 | X1 | X1 | X1 |
Table Overview
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