Acrylonitrile toxicity

Background

  • Unique type of Cyanide toxicity
  • Used in the production of plastics
    • Structure: Nitrile group linked to a Vinyl group

Mechanism of Action

  • Chemical itself is hepatotoxic
  • Also metabolized to form cyanide molecule

Clinical Features

Differential Diagnosis

Evaluation

Management

References

Authors:

Ross Donaldson