Difference between revisions of "Yellow fever"

(Stage 1: Infection)
(Stage 3: Intoxication)
 
Line 21: Line 21:
 
*[[Hepatic dysfunction]]
 
*[[Hepatic dysfunction]]
 
*[[Renal failure]]
 
*[[Renal failure]]
[Myocardial injury
+
*[[Acute coronary syndrome (main)|Myocardial injury]]
 
*CNS dysfunction
 
*CNS dysfunction
 
*Bleeding complications
 
*Bleeding complications

Latest revision as of 04:40, 20 November 2017

Background

  • A Flavi virus transmitted by Aedes and Haemagogus mosquitos
  • 200,000 cases per year with 30,000 deaths mostly in Africa
  • Endemic in tropical areas of sub-Sahara Africa and South America

Clinical Features

Stage 1: Infection

3-4 days of:

Stage 2: Remission

Either recovers or progresses to next stage in 48 hours

Stage 3: Intoxication

15% of patients Return of symptoms plus:

Differential Diagnosis

Fever in traveler

Evaluation

  • CBC
  • Chem
  • LFTs
  • Coags
  • Viral PCR
  • ELISA for IgM

Management

  • Symptomatic
  • Vaccination in endemic areas

Disposition

  • Admit

References