Difference between revisions of "Vitamin A deficiency"

(Created page with "==Background== *One of the most common vitamin deficiencies in developing countries *Most common cause of blindness in developing world *In US, most commonly found in conjunc...")
 
 
Line 2: Line 2:
 
*One of the most common vitamin deficiencies in developing countries
 
*One of the most common vitamin deficiencies in developing countries
 
*Most common cause of blindness in developing world  
 
*Most common cause of blindness in developing world  
*In US, most commonly found in conjunction with fat malabsorption syndromes (e.g. [[IBD]], pancreatic insufficiency, sprue, [[cystic fibrosis]], laxative abuse)
+
*In US, most commonly found in conjunction with fat malabsorption syndromes (e.g. [[IBD]], pancreatic insufficiency, sprue, [[cystic fibrosis]], [[bulimia nervosa|laxative abuse]])
  
 
==Clinical Features==
 
==Clinical Features==
Line 8: Line 8:
 
**Night blindness (early)
 
**Night blindness (early)
 
**Dry conjunctivae with small white patches (Bitot spots)
 
**Dry conjunctivae with small white patches (Bitot spots)
**Corneal ulceration/necrosis (keratomalacia), perforation, [[endophthalmitis]], and blindness (late)
+
**[[corneal ulcer|Corneal ulceration]]/necrosis (keratomalacia), perforation, [[endophthalmitis]], and blindness (late)
 
*Dry, hyperkeratinized skin, hair, and nails
 
*Dry, hyperkeratinized skin, hair, and nails
 
*[[Pruritus]]
 
*[[Pruritus]]

Latest revision as of 16:57, 29 September 2019

Background

  • One of the most common vitamin deficiencies in developing countries
  • Most common cause of blindness in developing world
  • In US, most commonly found in conjunction with fat malabsorption syndromes (e.g. IBD, pancreatic insufficiency, sprue, cystic fibrosis, laxative abuse)

Clinical Features

Differential Diagnosis

Acute Vision Loss (Noninflamed)

Emergent Diagnosis

Vitamin deficiencies

Evaluation

  • Eye exam
  • Serum Vitamin A level below 30–65 mg/dL

Management

  • Early: vitamin A 30,000 IU PO daily x 1 week
  • Advanced: vitamin A 20,000 IU/kg PO daily for at least 5 days

Disposition

See Also

External Links

References

Authors: