Trimethoprim-Sulfamethoxazole DS: Difference between revisions

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==Pharmacology==
==Pharmacology==
*Half-life:  
*Half-life: 6-12h (20-50h ESRD)
*Metabolism:  
*Metabolism:  
*Excretion:  
*Excretion:  
*Mechanism of Action:
*Mechanism of Action: Bactericidal


==Pregnancy/Lactation==
==Pregnancy/Lactation==

Revision as of 21:39, 19 February 2014

General

  • Type: Sulfonamide
  • Dosage Forms: 160/800
  • Common Trade Names: Bactrim DS

Adult Dosing

General

1 tab (160mg TMP) PO Q12h

PCP Prophylaxis

80-160mg TMP PO daily

PCP Treatment

15-20 mg/kg/day TMP PO divided q6-8h x 21 days

Pediatric Dosing

General (>2mo)

  • Mild-mod infection
    • 4-5 mg/kg TMP PO q12hr
  • Severe infection
    • 15-20 mg/kg/dy TMP PO divided q6-8h

Contraindications

  • Allergy to class/drug

Adverse Reactions

Pharmacology

  • Half-life: 6-12h (20-50h ESRD)
  • Metabolism:
  • Excretion:
  • Mechanism of Action: Bactericidal

Pregnancy/Lactation

  • Pregnancy:
  • Lactation:

See Also

Source