Trichuris trichiura: Difference between revisions
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==Differential Diagnosis== | ==Differential Diagnosis== | ||
{{Helminth Types}} | |||
==Workup== | ==Workup== | ||
==Management== | ==Management== | ||
*Albendazole | *Albendazole 400mg x 1 dose | ||
**Historically treated with albendazole or mebendazole, but monotherapy has low efficacy especially in heavy infections; higher cure rate achieved with oxantel pamoate-albendazole combination compared to any monotherapy in recent RCT <ref>Speich B, Ame S, et al. "Oxantel Pamoate–Albendazole for Trichuris Trichiura Infection." New England Journal of Medicine, 2014; 370: 610-620.</ref> | **Historically treated with albendazole or mebendazole, but monotherapy has low efficacy especially in heavy infections; higher cure rate achieved with oxantel pamoate-albendazole combination compared to any monotherapy in recent RCT <ref>Speich B, Ame S, et al. "Oxantel Pamoate–Albendazole for Trichuris Trichiura Infection." New England Journal of Medicine, 2014; 370: 610-620.</ref> | ||
*Iron supplements in [[anemia]] | *Iron supplements in [[anemia]] | ||
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==External Links== | ==External Links== | ||
== | ==References== | ||
<references/> | <references/> | ||
[[Category:ID]] | [[Category:ID]] | ||
[[Category: | [[Category:Tropical Medicine]] | ||
Latest revision as of 08:30, 21 July 2016
Background
Clinical Features
- Morbidity is related to number of worms harbored in intestines
- Light infections often asymptomatic
- Heavier infections with variety of manifestations including GI symptoms (abdominal pain, diarrhea, blood in stool, rectal prolapse), malaise, weakness, impaired cognitive / physical development, malnutrition[1]</ref>
- Iron-deficiency anemia
- Adult worms attach to intestinal wall to feed, causing ongoing luminal blood loss
Differential Diagnosis
Helminth infections
Cestodes (Tapeworms)
- Taenia saginata
- Taenia solium (Cysticercosis)
- Diphyllobothrium latum
- Hymenolepis nana
- Echinococcus granulosus
Trematodes (Flukes)
- Fasciola hepatica
- Fasciolopsis buski
- Opistorchis viverrini
- Schistosoma spp
- Chlonorchis sinensis
- Paragonimus spp.
Nematodes (Roundworms)
- Ascaris lumbricoides
- Enterobius vermicularis (Pinworm)
- Filarial worms
- Hookworm
- Necator americanus
- Ancylostoma duodenale
- Cutaneous larva migrans (Ancylostoma braziliense)
- Dracunculiasis
- Strongyloides stercoralis
- Trichuris trichiura (Whipworm)
- Anisakis
- Toxocara spp.
- Trichinosis
Workup
Management
- Albendazole 400mg x 1 dose
- Historically treated with albendazole or mebendazole, but monotherapy has low efficacy especially in heavy infections; higher cure rate achieved with oxantel pamoate-albendazole combination compared to any monotherapy in recent RCT [2]
- Iron supplements in anemia