Difference between revisions of "Trichuris trichiura"

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==Differential Diagnosis==
 
==Differential Diagnosis==
*[[Ascaris]]
+
{{Helminth Types}}
*[[Hookworm]]
 
  
 
==Workup==
 
==Workup==
  
 
==Management==
 
==Management==
*Albendazole 400 mg x 1 dose
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*Albendazole 400mg x 1 dose
 
**Historically treated with albendazole or mebendazole, but monotherapy has low efficacy especially in heavy infections; higher cure rate achieved with oxantel pamoate-albendazole combination compared to any monotherapy in recent RCT <ref>Speich B, Ame S, et al. "Oxantel Pamoate–Albendazole for Trichuris Trichiura Infection." New England Journal of Medicine, 2014; 370: 610-620.</ref>
 
**Historically treated with albendazole or mebendazole, but monotherapy has low efficacy especially in heavy infections; higher cure rate achieved with oxantel pamoate-albendazole combination compared to any monotherapy in recent RCT <ref>Speich B, Ame S, et al. "Oxantel Pamoate–Albendazole for Trichuris Trichiura Infection." New England Journal of Medicine, 2014; 370: 610-620.</ref>
 
*Iron supplements in [[anemia]]
 
*Iron supplements in [[anemia]]
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==External Links==
 
==External Links==
  
==Sources==
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==References==
 
<references/>
 
<references/>
  
 
[[Category:ID]]
 
[[Category:ID]]
[[Category:TropMed]]
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[[Category:Tropical Medicine]]

Latest revision as of 08:30, 21 July 2016

Background

Clinical Features

  • Morbidity is related to number of worms harbored in intestines
  • Light infections often asymptomatic
  • Heavier infections with variety of manifestations including GI symptoms (abdominal pain, diarrhea, blood in stool, rectal prolapse), malaise, weakness, impaired cognitive / physical development, malnutrition[1]</ref>
  • Iron-deficiency anemia
    • Adult worms attach to intestinal wall to feed, causing ongoing luminal blood loss

Differential Diagnosis

Helminth infections

Cestodes (Tapeworms)

Trematodes (Flukes)

Nematodes (Roundworms)

Workup

Management

  • Albendazole 400mg x 1 dose
    • Historically treated with albendazole or mebendazole, but monotherapy has low efficacy especially in heavy infections; higher cure rate achieved with oxantel pamoate-albendazole combination compared to any monotherapy in recent RCT [2]
  • Iron supplements in anemia

Disposition

See Also

External Links

References

  1. Wilcox S, Thomas S, Brown D, Nadel E. “Gastrointestinal Parasite.” The Journal of Emergency Medicine, 2007; 33(3):277-280
  2. Speich B, Ame S, et al. "Oxantel Pamoate–Albendazole for Trichuris Trichiura Infection." New England Journal of Medicine, 2014; 370: 610-620.