Difference between revisions of "Trazodone toxicity"

(Management)
 
Line 4: Line 4:
  
 
==Clinical Features==
 
==Clinical Features==
*CNS depression
+
*[[CNS Depression|CNS depression]]
 
**Most common symptom
 
**Most common symptom
**Rarely produces coma or seizures when it is the only drug ingested
+
**Rarely produces [[coma]] or [[seizures]] when it is the only drug ingested
*Respiratory depresion
+
*[[Respiratory distress|Respiratory depression]]
 
**Fairly common (but only with coingestants)
 
**Fairly common (but only with coingestants)
*Orthostatic hypotension
+
*Orthostatic [[hypotension]]
*QT prolongation
+
*[[QT prolongation]]
  
 
==Differential Diagnosis==
 
==Differential Diagnosis==
 +
{{Sedatve/hypnotic toxicity types}}
  
 
==Evaluation==
 
==Evaluation==
 +
*Clinical diagnosis, assess for alternate etiologies
  
 
==Management==
 
==Management==

Latest revision as of 01:23, 14 September 2019

Background

  • Trazodone is extremely safe in overdose as long as there are no coingestants
  • Has serotonergic and α blocking effects

Clinical Features

Differential Diagnosis

Sedative/hypnotic toxicity

Evaluation

  • Clinical diagnosis, assess for alternate etiologies

Management

Disposition

  • Consider discharge for patients who remain asymptomatic for at least 6 hours

See Also

References