Transplant complications: Difference between revisions

No edit summary
No edit summary
Line 9: Line 9:
**graft-versus-host disease
**graft-versus-host disease
**postoperative complications and complications of altered physiology secondary to the transplanted organ
**postoperative complications and complications of altered physiology secondary to the transplanted organ
*Often transplant patients present with common medical problems but require unique management due to their altered physiology
*Often transplant patients present with common medical problems but require unique management due to their altered physiology <ref>Tintinalli's</ref>
 
<ref>Tintinalli's</ref>
 
 


==Epidemiology==
*Types of presentations
**Infection (39%)
**Noninfectious GI/GU pathology (15%)
**Dehydration (15%)
**Electrolyte disturbances (10%)
**Cardiopulmonary pathology (10%)
**Injury (8%)
**Rejection (6%)
*Acute graft-versus-host disease occurs in 20% to 80% of patients post-hematopoietic stem cell transplantation (HSCT); rarely occurs in solid organ transplant <ref>Tintinalli's</ref>


<references/>
<references/>

Revision as of 18:45, 20 June 2015

Background

  • Transplanted organ frequency: kidney > liver > heart > lung > pancreas > other (combined and intestines)
    • First solid organ transplant was in 1954 (kidney)
  • Most transplant patients require lifelong immunosuppression
  • Types of emergencies
    • transplant-related infection
    • medication side effects
    • rejection
    • graft-versus-host disease
    • postoperative complications and complications of altered physiology secondary to the transplanted organ
  • Often transplant patients present with common medical problems but require unique management due to their altered physiology [1]

Epidemiology

  • Types of presentations
    • Infection (39%)
    • Noninfectious GI/GU pathology (15%)
    • Dehydration (15%)
    • Electrolyte disturbances (10%)
    • Cardiopulmonary pathology (10%)
    • Injury (8%)
    • Rejection (6%)
  • Acute graft-versus-host disease occurs in 20% to 80% of patients post-hematopoietic stem cell transplantation (HSCT); rarely occurs in solid organ transplant [2]
  1. Tintinalli's
  2. Tintinalli's