Difference between revisions of "Transplant complications"

Line 1: Line 1:
 
==Background==
 
==Background==
 
*Transplanted organ frequency: kidney > liver > heart > lung > pancreas > other (combined and intestines)
 
*Transplanted organ frequency: kidney > liver > heart > lung > pancreas > other (combined and intestines)
*Most transplant patients require lifelong immunosuppression
+
*Most transplant-related emergencies due to one of the following:
 +
**Infection
 +
**Medication side effect
 +
**[[Graft-versus-host disease]]
 +
**Postoperative complications (i.e.
 +
**Altered physiology due to transplanted organ
  
 
===Epidemiology===
 
===Epidemiology===
Line 24: Line 29:
 
*[[Pancreas transplant complications]]
 
*[[Pancreas transplant complications]]
 
*More severe or opportunistic infections due to immunocompromise
 
*More severe or opportunistic infections due to immunocompromise
 +
**May be afebrile due to immunosupression, have low treshhold for infectious work-up
  
 
==See Also==
 
==See Also==

Revision as of 20:16, 5 September 2016

Background

  • Transplanted organ frequency: kidney > liver > heart > lung > pancreas > other (combined and intestines)
  • Most transplant-related emergencies due to one of the following:
    • Infection
    • Medication side effect
    • Graft-versus-host disease
    • Postoperative complications (i.e.
    • Altered physiology due to transplanted organ

Epidemiology

  • Types of presentations
    • Infection (39%)
    • Noninfectious GI/GU pathology (15%)
    • Dehydration (15%)
    • Electrolyte disturbances (10%)
    • Cardiopulmonary pathology (10%)
    • Injury (8%)
    • Rejection (6%)
  • Acute graft-versus-host disease occurs in 20% to 80% of patients post-hematopoietic stem cell transplantation (HSCT); rarely occurs in solid organ transplant [1]

Immunosuppressant Medications

Types

See Also

External Links

References

  1. Tintinalli's