Difference between revisions of "Transplant complications"
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*Transplanted organ frequency: kidney > liver > heart > lung > pancreas > other (combined and intestines) | *Transplanted organ frequency: kidney > liver > heart > lung > pancreas > other (combined and intestines) | ||
*Most transplant patients require lifelong immunosuppression | *Most transplant patients require lifelong immunosuppression | ||
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===Epidemiology=== | ===Epidemiology=== | ||
Revision as of 19:49, 5 September 2016
Contents
Background
- Transplanted organ frequency: kidney > liver > heart > lung > pancreas > other (combined and intestines)
- Most transplant patients require lifelong immunosuppression
Epidemiology
- Types of presentations
- Infection (39%)
- Noninfectious GI/GU pathology (15%)
- Dehydration (15%)
- Electrolyte disturbances (10%)
- Cardiopulmonary pathology (10%)
- Injury (8%)
- Rejection (6%)
- Acute graft-versus-host disease occurs in 20% to 80% of patients post-hematopoietic stem cell transplantation (HSCT); rarely occurs in solid organ transplant [1]
Immunosuppressant Medications
- Balance between immune suppression, rejection and susceptibility to infection
- Typical regimen includes: calcineurin inhibitor + antimetabolite + steroid
- Calcineurin inhibitor
- Steroids
- +/- Antimetabolite
Types
- Graft-vs-host disease
- Kidney transplant complications
- Liver transplant complications
- Heart transplant complications
- Lung transplant complications
- Pancreas transplant complications
See Also
External Links
References
- ↑ Tintinalli's