Difference between revisions of "Transplant complications"

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**graft-versus-host disease
 
**graft-versus-host disease
 
**postoperative complications and complications of altered physiology secondary to the transplanted organ
 
**postoperative complications and complications of altered physiology secondary to the transplanted organ
*Often transplant patients present with common medical problems but require unique management due to their altered physiology
+
*Often transplant patients present with common medical problems but require unique management due to their altered physiology <ref>Tintinalli's</ref>
 
 
<ref>Tintinalli's</ref>
 
 
 
 
 
  
 +
==Epidemiology==
 +
*Types of presentations
 +
**Infection (39%)
 +
**Noninfectious GI/GU pathology (15%)
 +
**Dehydration (15%)
 +
**Electrolyte disturbances (10%)
 +
**Cardiopulmonary pathology (10%)
 +
**Injury (8%)
 +
**Rejection (6%)
 +
*Acute graft-versus-host disease occurs in 20% to 80% of patients post-hematopoietic stem cell transplantation (HSCT); rarely occurs in solid organ transplant <ref>Tintinalli's</ref>
  
 
<references/>
 
<references/>

Revision as of 18:45, 20 June 2015

Background

  • Transplanted organ frequency: kidney > liver > heart > lung > pancreas > other (combined and intestines)
    • First solid organ transplant was in 1954 (kidney)
  • Most transplant patients require lifelong immunosuppression
  • Types of emergencies
    • transplant-related infection
    • medication side effects
    • rejection
    • graft-versus-host disease
    • postoperative complications and complications of altered physiology secondary to the transplanted organ
  • Often transplant patients present with common medical problems but require unique management due to their altered physiology [1]

Epidemiology

  • Types of presentations
    • Infection (39%)
    • Noninfectious GI/GU pathology (15%)
    • Dehydration (15%)
    • Electrolyte disturbances (10%)
    • Cardiopulmonary pathology (10%)
    • Injury (8%)
    • Rejection (6%)
  • Acute graft-versus-host disease occurs in 20% to 80% of patients post-hematopoietic stem cell transplantation (HSCT); rarely occurs in solid organ transplant [2]
  1. Tintinalli's
  2. Tintinalli's