Difference between revisions of "Thromboangiitis obliterans"

(Clinical Features)
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==Clinical Features==
==Clinical Features==
[[File:PMC3371931 ircmj-13-420-g001.png|thumb]]
*Red, tender nodules over peripheral arteries
*Red, tender nodules over peripheral arteries
**May have diminished pulses
**May have diminished pulses

Revision as of 04:53, 5 June 2018


  • Also known as "Buerger's disease"
  • Idiopathic inflammatory occlusive disease of the hands and feet (exact pathogenesis unknown)
  • Risk factors: Male, tobacco users, Middle Eastern
    • Virtually all affected patients are smokers

Clinical Features

PMC3371931 ircmj-13-420-g001.png
  • Red, tender nodules over peripheral arteries
    • May have diminished pulses
  • In-step claudication
  • Hand claudication
    • Often bilateral and symmetrical
    • May lead to ulceration

Differential Diagnosis


  • Clinical criteria for diagnosis (noninvasive testing not necessary)
    • History of smoking
    • Onset prior to <50 years old
    • Absence of atherosclerotic risk factors
    • Upper limb involvement
    • Infrapopliteal arterial occlusive lesions


  • Abstinence from tobacco
  • Early symptoms with out threatened tissue loss: outpatient vascular
  • Advanced disease: intra-arterial or intravenous PGE1, ASA, Heparin, arterial reconstruction, sympathectomy


  • Discharge with vascular follow-up if no evidence/threat of tissue loss
  • Otherwise admit

See Also

External Links