Difference between revisions of "Thromboangiitis obliterans"

(Clinical Features)
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==Clinical Features==
==Clinical Features==
*Red, tender nodules over peripheral arteries
**+/- diminished pulses
*In-step claudication
*Hand claudication
**Often bilateral & symmetrical
**May lead to ulceration
==Differential Diagnosis==
==Differential Diagnosis==

Revision as of 15:54, 6 February 2017


  • AKA Thromboangiitis Obliterates


  • Idiopathic inflammatory occlusive disease of the hands and feet
    • Exact pathogenesis unknown

Risk Factors

  • Male, tobacco, Middle Eastern
    • Virtually all patients are smokers

Clinical Features

  • Red, tender nodules over peripheral arteries
    • +/- diminished pulses
  • In-step claudication
  • Hand claudication
    • Often bilateral & symmetrical
    • May lead to ulceration

Differential Diagnosis


  • Clinical criteria for Dx (noninvasive testing not necessary)
    • History of smoking
    • Onset prior to <50 y/o
    • Absence of atherosclerotic risk factors
    • Upper limb involvement
    • Infrapopliteal arterial occlusive lesions


  • Abstinence from tobacco
  • Early symptoms w/o threatened tissue loss: outpatient vascular
  • Advanced disease: intra-arterial or intravenous PGE1, ASA, Heparin, arterial reconstruction, sympathectomy


See Also

External Links