Difference between revisions of "Thromboangiitis obliterans"

(Background)
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*Also known as "Buerger's disease"
 
*Also known as "Buerger's disease"
 
*Idiopathic inflammatory occlusive disease of the hands and feet (exact pathogenesis unknown)
 
*Idiopathic inflammatory occlusive disease of the hands and feet (exact pathogenesis unknown)
*Risk factors: Male, tobacco users, Middle Eastern
+
 
 +
===Risk factors===
 +
*Tobacco use
 
**Virtually all affected patients are smokers
 
**Virtually all affected patients are smokers
 +
*Male
 +
*Middle Eastern
  
 
==Clinical Features==
 
==Clinical Features==

Revision as of 05:01, 5 June 2018

Background

  • Also known as "Buerger's disease"
  • Idiopathic inflammatory occlusive disease of the hands and feet (exact pathogenesis unknown)

Risk factors

  • Tobacco use
    • Virtually all affected patients are smokers
  • Male
  • Middle Eastern

Clinical Features

PMC3371931 ircmj-13-420-g001.png
  • Red, tender nodules over peripheral arteries
    • May have diminished pulses
  • In-step claudication
  • Hand claudication
    • Often bilateral and symmetrical
    • May lead to ulceration

Differential Diagnosis

Blue Digit

Evaluation

  • Clinical criteria for diagnosis (noninvasive testing not necessary)
    • History of smoking
    • Onset prior to <50 years old
    • Absence of atherosclerotic risk factors
    • Upper limb involvement
    • Infrapopliteal arterial occlusive lesions

Management

  • Abstinence from tobacco
  • Early symptoms with out threatened tissue loss: outpatient vascular
  • Advanced disease: intra-arterial or intravenous PGE1, ASA, Heparin, arterial reconstruction, sympathectomy

Disposition

  • Discharge with vascular follow-up if no evidence/threat of tissue loss
  • Otherwise admit

See Also

External Links

References