Template:Serotonin syndrome vs neuroleptic malignant syndrome

Revision as of 04:33, 13 February 2017 by Mholtz (talk | contribs) (Serotonin syndrome vs Neuroleptic malignant syndrome)
(diff) ← Older revision | Latest revision (diff) | Newer revision → (diff)

Serotonin syndrome vs Neuroleptic malignant syndrome

  • History of a new serotonergic drug or a dose increase of a serotonergic drug are helpful
  • Serotonin syndrome is usually much more acute in onset than NMS which may develop over days or weeks
  • Presence of ‘lead pipe’ rigidity is typical of NMS, while serotonin syndrome typically manifests with tremor and hyperreflexia
  • Elevations in CK, LFTs, and WBC, coupled with a low iron level, distinguishes NMS from serotonin syndrome among patients taking both neuroleptic and serotonin agonist medications simultaneously