Template:Meningitis Antibiotics

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treatment guidelines based on van de Beek et al[1]

Neonates (up to 1 month of age)

MRSA is uncommon in the neonate

> 1 month to Adult

Vancomycin is for resistant [Pneumococcus]])

Post Procedural (or penetrating trauma)

Cryptococcosis Meningitis

Options

  • Amphotericine B 1mg/kg IV once daily AND Fluctosine 25mg/kg PO q6hrs daily
  • Amphotericine B 5mg/kg IV once daily AND Flucytosine 25mg/kg PO q6hrs daily

Neisseria meningitidis Prophylaxis

  • [[Ceftriaxone 250mg IM once (if less than 15yo then 125mg IM)
  • Ciprofloxacin 500mg PO once
  • Rifampin 600 mg PO BID x 2 days
    • if < 1 month old then 5mg/kg PO BID x 2 days
    • if ≥ 1 month old then 10mg/kg (max at 600mg) PO BID x 2 days

Meningitis with severe PCN allergy

Age >50y

  1. van de Beek D. et al. Advances in treatment of bacterial meningitis. Lancet. Nov 10 2012;380(9854):1693-702