Template:BNP value

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Brain natriuretic peptide (BNP)

  • <100 CHF ruled out (Sn 90%, NPV 89%)
  • 100-500: Consider differential diagnosis and pre-test probability
  • > 500 Positive (CHF Sp 87%, PPV 90%)

Differential Diagnosis (Elevated BNP)

May have false negatives with obesity and diastolic dysfunction

Utility

  • Obtaining BNP value may not add anything to patient centered outcomes[1]
  • May be used to gauge treatment response in acute decompensated CHF
  • Carpenter CR et al. BRAIN NATRIURETIC PEPTIDE IN THE EVALUATION OF EMERGENCY DEPARTMENT DYSPNEA: IS THERE A ROLE? J Emerg Med. 2012 Feb; 42(2): 197–205.