Template:BNP value: Difference between revisions
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*> 500 Positive ([[CHF]] Sp 87%, PPV 90%) | *> 500 Positive ([[CHF]] Sp 87%, PPV 90%) | ||
==== Differential Diagnosis (Elevated BNP)==== | ====Differential Diagnosis (Elevated BNP)==== | ||
* [[CHF]]/[[ACS]]/[[Cardiogenic shock]] | * [[CHF]]/[[ACS]]/[[Cardiogenic shock]] | ||
* [[PE]] | * [[PE]] | ||
* [[Pulmonary Hypertension]] | * [[Pulmonary Hypertension]] | ||
* [[Renal Failure]] | * [[Renal Failure]] | ||
* [[LVH]] | |||
* [[Subarachnoid hemorrhage]] | |||
''May have false negatives with obesity and diastolic dysfunction'' | ''May have false negatives with obesity and diastolic dysfunction'' | ||
====Utility==== | |||
*Obtaining BNP value may not add anything to patient centered outcomes<ref>Carpenter CR et al. BRAIN NATRIURETIC PEPTIDE IN THE EVALUATION OF EMERGENCY DEPARTMENT DYSPNEA: IS THERE A ROLE? J Emerg Med. 2012 Feb; 42(2): 197–205.</ref> | |||
*May be used to gauge treatment response in acute decompensated CHF | |||
Revision as of 11:08, 1 June 2016
Brain natriuretic peptide (BNP)
- <100 CHF ruled out (Sn 90%, NPV 89%)
- 100-500: Consider differential diagnosis and pre-test probability
- > 500 Positive (CHF Sp 87%, PPV 90%)
Differential Diagnosis (Elevated BNP)
May have false negatives with obesity and diastolic dysfunction
Utility
- Obtaining BNP value may not add anything to patient centered outcomes[1]
- May be used to gauge treatment response in acute decompensated CHF
- ↑ Carpenter CR et al. BRAIN NATRIURETIC PEPTIDE IN THE EVALUATION OF EMERGENCY DEPARTMENT DYSPNEA: IS THERE A ROLE? J Emerg Med. 2012 Feb; 42(2): 197–205.