Difference between revisions of "Template:BNP value"

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*> 500 Positive ([[CHF]] Sp 87%, PPV 90%)  
 
*> 500 Positive ([[CHF]] Sp 87%, PPV 90%)  
  
==== Differential Diagnosis (Elevated BNP)====
+
====Differential Diagnosis (Elevated BNP)====
 
* [[CHF]]/[[ACS]]/[[Cardiogenic shock]]
 
* [[CHF]]/[[ACS]]/[[Cardiogenic shock]]
 
* [[PE]]
 
* [[PE]]
 
* [[Pulmonary Hypertension]]
 
* [[Pulmonary Hypertension]]
 
* [[Renal Failure]]
 
* [[Renal Failure]]
 +
* [[LVH]]
 +
* [[Subarachnoid hemorrhage]]
  
 
''May have false negatives with obesity and diastolic dysfunction''
 
''May have false negatives with obesity and diastolic dysfunction''
 +
 +
====Utility====
 +
*Obtaining BNP value may not add anything to patient centered outcomes<ref>Carpenter CR et al. BRAIN NATRIURETIC PEPTIDE IN THE EVALUATION OF EMERGENCY DEPARTMENT DYSPNEA: IS THERE A ROLE? J Emerg Med. 2012 Feb; 42(2): 197–205.</ref>
 +
*May be used to gauge treatment response in acute decompensated CHF

Revision as of 11:08, 1 June 2016

Brain natriuretic peptide (BNP)

  • <100 CHF ruled out (Sn 90%, NPV 89%)
  • 100-500: Consider differential diagnosis and pre-test probability
  • > 500 Positive (CHF Sp 87%, PPV 90%)

Differential Diagnosis (Elevated BNP)

May have false negatives with obesity and diastolic dysfunction

Utility

  • Obtaining BNP value may not add anything to patient centered outcomes[1]
  • May be used to gauge treatment response in acute decompensated CHF
  • Carpenter CR et al. BRAIN NATRIURETIC PEPTIDE IN THE EVALUATION OF EMERGENCY DEPARTMENT DYSPNEA: IS THERE A ROLE? J Emerg Med. 2012 Feb; 42(2): 197–205.