Strychnine

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Background

Strychnine is a highly toxic substance, mimics generalized tetanus. Antagonizes glycine release, but unlike TS, it has no effect on GABA release.

Clinical Features

Differential Diagnosis

  • generalized tetanus
  • Black widow spider bite
  • stiff-man syndrome

Jaw Spasms

Diagnosis

  • Serum and urine tests for strychnine

Management

Disposition

  • All patients should be admitted

See Also

References

rosen, 7th edition p1684

http://en.wikipedia.org/wiki/Strychnine#Symptoms