Difference between revisions of "Stevens-Johnson syndrome and toxic epidermal necrolysis"

Line 13: Line 13:
  
 
==Work-Up==
 
==Work-Up==
 
+
*CBC
 +
*Chem
 +
*ESR
 +
*CXR
 
==Treatment==
 
==Treatment==
 
*Removal of inciting cause if identified
 
*Removal of inciting cause if identified

Revision as of 19:43, 2 February 2012

Background

  • SJS and TEN involve IC-mediated cell death w/ separation of epidermis from dermis
    • SJS involves <10% of BSA
    • TEN involves >30% of BSA

Diagnosis

  • Often have prodrome (fever, URI symptoms, HA, malaise)
  • Rash begins suddenly
    • Target lesions
  • Mucous membranes can be severely affected
    • Eye involvement can be severe
  • In severe cases, respiratory tract and GI involvement may occur

Work-Up

  • CBC
  • Chem
  • ESR
  • CXR

Treatment

  • Removal of inciting cause if identified
  • Treat shock w/ IV fluids according to burn protocols

Disposition

  • Admit to burn unit or ICU

Source

Tintinalli