Sequential (Sepsis Related) Organ Failure Assessment Score (SOFA): Difference between revisions
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==See Also== | |||
*[[Quick Sequential (Sepsis Related) Organ Failure Assessment Score (qSOFA)]] | |||
==External Links== | ==External Links== | ||
Revision as of 13:39, 11 May 2016
Background
The SOFA score is a scoring system to determine the extent of a person's organ function or rate of failure.[1][2][3] The score is based on six different scores based on the organ system involved. Use the worst value in a 24-hour period.
Predicting Outcomes
Both the mean and highest SOFA scores being predictors of outcome.
- An increase in SOFA score during the first 24 - 48 hours in the ICU predicts a mortality rate of at least 50% up to 95%. Scores less than 9 give predictive mortality at 33% while above 11 can be close to or above 95%[4]
- A SOFA score ≥2 reflects an overall mortality risk of approximately 10% in a general hospital population with suspected infection[5]
Respiratory System
| PaO2/FiO2 (mmHg) | SOFA score |
|---|---|
| < 400 | 1 |
| < 300 | 2 |
| < 200 and mechanically ventilated | 3 |
| < 100 and mechanically ventilated | 4 |
Nervous System
| Glasgow Coma Scale (GCS) | SOFA score |
|---|---|
| 13–14 | 1 |
| 10–12 | 2 |
| 6–9 | 3 |
| < 6 | 4 |
Cardio Vascular System
| Mean Arterial Pressure OR administration of vasopressors required | SOFA score |
|---|---|
| MAP < 70 mm/Hg | 1 |
| Dopamine drip <= 5 or Dobutamine (any dose) |
2 |
| Dopamine >5 or Epinephrine <=0.1 or Norepinephrine <=0.1 |
3 |
| Dopamine >15 or Epinephrine >0.1 or Norepinephrine >0.1 |
4 |
vasopressor doses are all in µg/kg/min
Liver
| Bilirubin (mg/dl) [μmol/L] | SOFA score |
|---|---|
| 1.2–1.9 [> 20-32] | 1 |
| 2.0–5.9 [33-101] | 2 |
| 6.0–11.9 [102-204] | 3 |
| > 12.0 [> 204] | 4 |
Coagulation
| Platelets×103/µl | SOFA score |
|---|---|
| < 150 | 1 |
| < 100 | 2 |
| < 50 | 3 |
| < 20 | 4 |
Renal System
| Creatinine (mg/dl) [μmol/L] (or urine output) | SOFA score |
|---|---|
| 1.2–1.9 [110-170] | 1 |
| 2.0–3.4 [171-299] | 2 |
| 3.5–4.9 [300-440] (or < 500 ml/d) | 3 |
| > 5.0 [> 440] (or < 200 ml/d) | 4 |
See Also
External Links
References
- ↑ Vincent JL et al. The SOFA (Sepsis-related Organ Failure Assessment) score to describe organ dysfunction/failure. On behalf of the Working Group on Sepsis-Related Problems of the European Society of Intensive Care Medicine. Intensive Care Med 1996 Jul;22(7):707-10. PMID 8844239.
- ↑ Ferreira FL et al. Serial evaluation of the SOFA score to predict outcome in critically ill patients. JAMA 2001 Oct 10;286(14):1754-8. PMID 11594901
- ↑ de Mendonça A et al. Acute renal failure in the ICU: risk factors and outcome evaluated by the SOFA score. Intensive Care Med 2000 Jul;26(7):915-21. PMID 10990106
- ↑ Vincent JL, et al; Working Group on “Sepsis-Related Problems” of the European Society of Intensive Care Medicine. Use of the SOFA score to assess the incidence of organ dysfunction/failure in intensive care units: results of a multicenter, prospective study. Crit Care Med. 1998;26(11):1793-1800.
- ↑ Singer, M et al. The Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3). JAMA. 2016;315(8):801-810.