Difference between revisions of "Ranitidine"

(Special Populations)
(Contraindications)
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==Contraindications==
 
==Contraindications==
 
*Allergy to class/drug
 
*Allergy to class/drug
 +
* Porphyria
 +
* caution if hepatic impairment
 +
* caution if renal impairment
 +
* caution if chronic pulmonary disease
 +
* caution if diabetes mellitus
 +
* caution if immunocompromised
  
 
==Adverse Reactions==
 
==Adverse Reactions==

Revision as of 20:04, 28 March 2015

General

  • Type: H2 Blocker
  • Dosage Forms: 75, 150, 300
  • Common Trade Names: Zantac

Adult Dosing

GERD: 150 mg PO BID

Pediatric Dosing

GERD: 5-10 mg/kg/day PO BID

Special Populations

  • Pregnancy Rating: B
  • Lactation: Probably Safe
  • Renal Dosing
    • Adult: CrCl < 50: 150 mg Qday; CrCl < 10: 75 -150 mg Qday; HD: give dose after dialysis
    • Pediatric: CrCl < 10-50: decrease dose 50%; CrCl< 10: decrease dose 75%; HD: Give dose after dialysis
  • Hepatic Dosing
    • Adult: Not defined
    • Pediatric: not defined

Contraindications

  • Allergy to class/drug
  • Porphyria
  • caution if hepatic impairment
  • caution if renal impairment
  • caution if chronic pulmonary disease
  • caution if diabetes mellitus
  • caution if immunocompromised

Adverse Reactions

Serious

Common

Pharmacology

  • Half-life:
  • Metabolism:
  • Excretion:
  • Mechanism of Action:

See Also

Sources