Difference between revisions of "Ranitidine"

(Pediatric Dosing)
(Special Populations)
Line 11: Line 11:
  
 
==Special Populations==
 
==Special Populations==
*[[Drug Ratings in Pregnancy|Pregnancy Rating]]:
+
*[[Drug Ratings in Pregnancy|Pregnancy Rating]]: B
*Lactation:
+
*Lactation: Probably Safe
 
*Renal Dosing
 
*Renal Dosing
**Adult
+
**Adult: CrCl < 50: 150 mg Qday; CrCl < 10: 75 -150 mg Qday; HD: give dose after dialysis
**Pediatric
+
**Pediatric: CrCl < 10-50: decrease dose 50%; CrCl< 10: decrease dose 75%; HD: Give dose after dialysis
 
*Hepatic Dosing
 
*Hepatic Dosing
**Adult
+
**Adult: Not defined
**Pediatric
+
**Pediatric: not defined
  
 
==Contraindications==
 
==Contraindications==

Revision as of 20:02, 28 March 2015

General

  • Type: H2 Blocker
  • Dosage Forms: 75, 150, 300
  • Common Trade Names: Zantac

Adult Dosing

GERD: 150 mg PO BID

Pediatric Dosing

GERD: 5-10 mg/kg/day PO BID

Special Populations

  • Pregnancy Rating: B
  • Lactation: Probably Safe
  • Renal Dosing
    • Adult: CrCl < 50: 150 mg Qday; CrCl < 10: 75 -150 mg Qday; HD: give dose after dialysis
    • Pediatric: CrCl < 10-50: decrease dose 50%; CrCl< 10: decrease dose 75%; HD: Give dose after dialysis
  • Hepatic Dosing
    • Adult: Not defined
    • Pediatric: not defined

Contraindications

  • Allergy to class/drug

Adverse Reactions

Serious

Common

Pharmacology

  • Half-life:
  • Metabolism:
  • Excretion:
  • Mechanism of Action:

See Also

Sources