Proctitis: Difference between revisions

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===[[Gonorrhea]]===
===[[Gonorrhea]]===
*Symptoms vary from none to severe rectal pain w/ yellow, bloody discharge
*Symptoms vary from none to severe rectal pain with yellow, bloody discharge
*Unlike nonvenereal cryptitis, infection is not confined to the posterior crypt
*Unlike nonvenereal cryptitis, infection is not confined to the posterior crypt
*Diagnosis made by Gram stain and culture
*Diagnosis made by Gram stain and culture
*Also consider dissemination to heart, liver, CNS, and joints
*Also consider dissemination to heart, liver, CNS, and joints
*Treatment: [[ceftriaxone]] 125mg IM + azithromycin 2gm PO single dose
*Treatment: [[ceftriaxone]] 125mg IM + [[azithromyci]]n 2gm PO single dose


===[[Chlamydia]]===
===[[Chlamydia]]===
*Infection d/t direct anorectal infection or via vaginal seeding to perirectal lymphatics
*Infection due to direct anorectal infection or via vaginal seeding to perirectal lymphatics
*Symptoms range from asymptomatic to anal pruritus, pain, purulent discharge
*Symptoms range from asymptomatic to anal pruritus, pain, purulent discharge
*Lymphogranulomatous variety
*Lymphogranulomatous variety
**Acutely painful anal ulcerations a/w unilateral lymph node enlargement
**Acutely painful anal ulcerations a/w unilateral lymph node enlargement
**Fever and flulike symptoms
**[[Fever]] and flulike symptoms
**May result in rectal scarring, stricturing, perirectal abscesses, chronic fistulas
**May result in rectal scarring, stricturing, perirectal abscesses, chronic fistulas
*Treatment
*Treatment
**Non-LGV: Azithromycin 2gm PO x1 or doxycycline 100mg PO BID x7d
**Non-LGV: [[Azithromycin]] 2gm PO x1 or [[doxycycline]] 100mg PO BID x7d
**LGV: Doxycyline 100mg PO BID x21d
**LGV: [[Doxycyline]] 100mg PO BID x21d
===[[Syphilis]]===
===[[Syphilis]]===
*Primary
*Primary
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**Condylomata lata (flatter and firmer than condylomata acuminata)
**Condylomata lata (flatter and firmer than condylomata acuminata)
*Treatment
*Treatment
**Penicillin G 2.4mil IM x1
**[[Penicillin]] G 2.4mil IM x1
===[[Herpes Simplex Virus-2]]===
===[[Herpes Simplex Virus-2]]===
*Itching and soreness in perianal area progressing to severe anorectal pain
*Itching and soreness in perianal area progressing to severe anorectal pain
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**Vesicles then enlarge, coalesce, and rupture, forming exquisitely tender ulcers
**Vesicles then enlarge, coalesce, and rupture, forming exquisitely tender ulcers
*Treatment
*Treatment
**Acyclovir 400mg PO TID x10d for initial episode; 800mg TID x2d for recurrent episodes
**[[Acyclovir]] 400mg PO TID x10d for initial episode; 800mg TID x2d for recurrent episodes


==See Also==
==See Also==

Revision as of 06:59, 30 August 2015

Background

Causes

  • Radiation tx
  • Autoimmune
  • Vasculitis
  • Ischemia
  • Infectious (STI and enteric organisms)

Clinical Features

  • Inflammation of the rectal mucosa

Differential Diagnosis

Anorectal Disorders

Diagnosis and Treatment

Condyloma Acuminata

Gonorrhea

  • Symptoms vary from none to severe rectal pain with yellow, bloody discharge
  • Unlike nonvenereal cryptitis, infection is not confined to the posterior crypt
  • Diagnosis made by Gram stain and culture
  • Also consider dissemination to heart, liver, CNS, and joints
  • Treatment: ceftriaxone 125mg IM + azithromycin 2gm PO single dose

Chlamydia

  • Infection due to direct anorectal infection or via vaginal seeding to perirectal lymphatics
  • Symptoms range from asymptomatic to anal pruritus, pain, purulent discharge
  • Lymphogranulomatous variety
    • Acutely painful anal ulcerations a/w unilateral lymph node enlargement
    • Fever and flulike symptoms
    • May result in rectal scarring, stricturing, perirectal abscesses, chronic fistulas
  • Treatment

Syphilis

  • Primary
    • Anal chancres are often painful
      • May be misdiagnosed as simple fissure
        • Symmetric lesion on opposite side of anal margin is distinguishing feature
        • Inguinal adenopathy is often present
  • Secondary
    • Condylomata lata (flatter and firmer than condylomata acuminata)
  • Treatment

Herpes Simplex Virus-2

  • Itching and soreness in perianal area progressing to severe anorectal pain
    • Accompanied by flulike illness, inguinal adenopathy
  • Early lesions are small, discrete vesicles on erythematous base
    • Vesicles then enlarge, coalesce, and rupture, forming exquisitely tender ulcers
  • Treatment
    • Acyclovir 400mg PO TID x10d for initial episode; 800mg TID x2d for recurrent episodes

See Also

References